Coxiella Burnetii "Q-FEVER", Ehrlichia chaffeensis

Question 1

clinical Syndrom of Coxiella burnetii

Answer 1

“Q-FEVER”

Question 2

Transmission of Coxiella Burnetii

Answer 2

Question 3

diagnosis of Coxiella Burnetti

Answer 3

gram (-) coccobacillus

Question 4

the 2 phases of Coxiella Burnetii

Answer 4

phase l : the virulent form
phase ll : Avirulent form (resistant)

Question 5

clincial manifestaions of Coxiella Burnetii

Answer 5

1) Acute infection –>
- self-limted febril flu-like illness
- Atypical Pneumonia

2) infection in pregnancy –> abortion during the 1st
trimester

3) Chronic Q-fever –> Endocarditis- VASCULAR PROSTHESIS & ANEURYSM INFECTIONS

*Chronic Q-fever Endocarditis –> 100% fatal if untreated

Question 6

diagnosis of Acute infection caused by Coxilla burnetii

Answer 6

PHASE ll antibodies
Serology –> 4-fold increase in IgG phase ll titers

Question 7

Diagnosis of Chronic infection
caused by Coxella Burnetii

Answer 7

Phase l antibodies
–> immunihistochemistry, culture, serology, PCR

Question 8

Transmission of Ehrlichia chaffeensis

Answer 8

Zoonoses, tick, “white tailed deer”

Question 9

Transmission of Anoplasmosis Phagocytophilum

Answer 9

“white footed mouse”–> humans are accidental hosts w/ bite of Ixodes spp ticks