Capnocytophaga canimorsus, pasterulla spp. , Yersinia pestis "plaque", Francisella tularenisis, bartonella spp

Question 1

Transmission of Capnocytophaga
canimorsus

Answer 1

dog bites or into skin abrasions (dog licking skin wounds)

Question 2

Clinical syndroms of Capnocytophaga
canimorsus

Answer 2

• Septicaemia & septic shock
  –> sepsis & shock w/ purpura fulminans of symmetric gangrene

Question 3

who is at danger from infections caused by Capnocytophaga canimorsus

Answer 3

Splenectomy patients –> in great DANGER

Question 4

Transmission of Yersinia Pestis

Answer 4

Zoonoses: flea bites, contact/secretions of infected animals, aerosols (from persons
with pneumonic plague)

Question 5

clinical syndrom of Yersinia pestis

Answer 5

1) Septicaemia plaque “ BALCK DEATH –> 100% untreated
- sudden fever w/o localized symptoms
- Rapid progressiong - overwhelming spesis -death from multiple organ failure

2) Bubonic plaque - “BUBOES” –> 50% if untreated
- high fever w/ lymp node sweeling
- Bacteraemia
- Groin/ Axila Buboes

3) Penuomonic plaque
primary :inhalation of Y.pesitis
secondary (most common): Haemotogenous spread from buboes
–> fatal in 3-6 days & potentially contagious –> ISOLATION

Question 6

Transmission of Pasterurella spp

Answer 6

scartches or bites or licking (open wounds) from dogs or especially cats

Question 7

clinical manifesations of Pasteurella spp

Answer 7

1) skin and soft tissue infections w/ purulent discharge
2) septic arthritis & osteomylitis

Question 8

Important

Transmission of Francisella tularensis

Answer 8

Zoonoses: lagomorphs, squirrels, beavers, mice, hares

	*no human-human transmission** 

*Animal contact: skinning (hunters), eating infected animals, animal bites

Question 9

clinical manifestions of Francisella Tularensis

Answer 9

1) Ulceroglandular (most common)
–> painful unlcers w/ raised borders (after tick bites) and regional lymphasenitis

2) Oculoglandular –> Conjunctivitis & Cervical tender adenopathy

3) Oropharyngeal –> fever & pharyngitis/ tonsilitis

4) Pneumonic –> high moratality

5) glandular –> adenopathy w/o localized symptoms
6) typhoidal –> febril illness , can be dramatic

Question 10

exam Q

clinical manifestations of Bartonella Henselae

Answer 10

“Cat scartch disease
1) regional lymphodenopathy
2) in rare cases –>
FUO (fever of unknown origin) –> Bacteraemia & infective Endocarditis
3) Bacillary angiomatosis :skin &internal organs, hepatic peliosis, spleen peliosis

Question 11

CM of Bartonella bacilliformis

Answer 11

“Oroya fever”
- Fever, mental status changes, sever aneamia
–> end organ ischeamia from aneamia
- Aysmptomatic persistence of bactereamia in 15%

Verrgua peruana
- skin infection –> mulaire lesions, vascualr skin lesions filled w/ blood

Question 12

Transmission of Bartonella bacilliformis

Answer 12

Zoonoses: sandflies

Question 13

Transmission of Bartonella quintana

Answer 13

Zoonoses: human body lice

Question 14

clinical syndrom of Bartonella quintana

Answer 14

“Trench fever”
–> in HIV & immunocompromised:
bacteraemia & bacillary angiomatosis (peliosis): neovascular lesions