Covid 19 & Pandemic Flashcards
Covid-19 Full Name
Coronavirus Disease 2019
Covid-19 Cause
SARS-CoV-2
Severe Acute Respiratory Syndome Coronavirus 2
Virus Structure
Capsid enclosing nucleic acid and envelope containing surface proteins
SARS CoV-2 Structure
Single stranded RNA and spike glycoprotein
Covid-19 Life Cycle?
Covid-19 enters the body–>membrane fusion–>DNA release–>Translation–>RND replication–>Translational–>RNA packing–>(ACE2-enabling entrance of the virus into cells and causing the infection)
Major Types of Covid-19 Testing Methods
Nucleic Acid Test: Detects the virus genetic material to
Antibody Testing: Detects if the body has produced antibodies, indicates past infection
Antigen Test: Looks for fragments of viral protein
Virus Classification
based on nucleid acid content
dsDNA viruses
ssDNA viruses
dsRNA viruses
(+) and (-) ssRNA viruses
ssRNA-RT viruses
dsDNA-RT viruses
Baltimore Classification. ds: double stranded
Inmune response caused by a virus infection and vaccination
Include Antibody production and cell mediaed immunity
When your body detects an antigen, it releases antibodies that bind to them, neutralizing it.
Cell Mediaded Immunity kills infected cell.
Antibody Mediaded Immunity neutralizes virus.
RNA vaccines
How are they made
A transcription rxn is run with enzymes and RNA nucleotides to produce RNA from a plasmid DNA template. The RNA is then purified and encapsulate in lipid nanoparticles to protect it.