Cortical Dementia - Frontotemporal Dementia

Question 1

Frontotemporal dementia

Answer 1

degeneration of frontal and temporal lobes

Question 2

Includes

Answer 2

Pick’s disease, progressive non-fluent aphasia, semantic dementia

Question 3

Pick’s disease

Answer 3

Personality changes, antisocial and inappropriate behavior, and memory loss in absence of language deficits

Question 4

Neuropathology

Answer 4

Pick bodies and ballooned neurons

Results in shrinkage of frontal and temporal lobes

No amyloid plaques or neurofibrillary tangles

Question 5

PPAs

Answer 5

PPAs - language function declines before cognitive deficits appear

Pick’s disease - cognitive and personality changes precede decline language