Coronaviridae Flashcards

1
Q

Qué virus son

A

Coronavirus

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2
Q

Características

A

Son virus envueltos, helicoidales, de ARN monocatenario + no segmentado

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3
Q

Cuáles infectan a humano?

A
  • 4, (OC43, 2296, NL63 y HKU1), causan el 10-30% de las infecciones rptas del resfriado común
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4
Q

Cuáles son zoonóticos

A
  • 3 (SARS, MER, SDRD-2)
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5
Q

SARS

A
  • Murciélago- Civetas (P-P)
  • Se une al receptor ACE2 = afecta al ep rpto, IG y endotelio
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6
Q

MERS

A
  • Murciélago - Dromedarios (Camello-P)
  • Afecta a DPP4 = Ep rpto, ID, hígado y riñones
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7
Q

SARS-2

A
  • ¿Murciélago–?- P-P
  • ACE2= Ep rpto, ID, endotelio
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8
Q

Qué producen los 3 virus zoonóticos

A

SDRA = Sepsis (- SARS-2) y FMO

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9
Q

Dco

A

Test antigénicos

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10
Q

Tto SARS-COV-2

A

-Nirmatrelvir/ritonavir = inhibe proteasa viral
-Molnupiravir = interfiere con ARN polimerasa

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