COPD Flashcards
What is it
COPD is characterised by airflow obstruction which is progressive in severity. not fully reversible. umbrella term for emphysema, chronic bronchitis- can occur without airflow obstruction, asthma
inflammation and symptoms in COPD
systemic inflammation- leads to problems alongside lung inflammation. other symptoms- weight loss, skeletal muscle dysfunction, cardiovascular disease, osteoarthritis, depression and fatigue, cancer
normal airway clearance
airways line by- cells which produce mucus, tiny hair cells called cilia which continually beats. mucus traps dust particles and bacteria. the cilia move the mucus along until it reaches the throat, and we swallow it or cough. defence mechanisms
what can go wrong with airway clearance
In COPD and bronchiectasis excess mucus is produced, mucus is thicker and stickier. the cilia are unable to beat, smoking paralyses the cilia. therefore, dust and bacteria stay trapped in the airways. mucus builds up providing a warm moist environment for bacteria to grow- recurrent chest infection
whatsis bronchitis
chronic disease of lungs where bronchi become inflamed. the inflammation causes mucus to be produced, which narrows the airways and makes breathing more difficult. increased sputum production- over production of mucus in the airways which becomes difficult to clear
bronchitis symptoms
wheezing is common especially after coughing. this Is because the inflamed airways may narrow for short period. this reduces the amount of air that enters the lungs. airways may be inflamed. airways are narrower with less space for sputum to get through. as a result, may feel unwell, tired and unable to cough
what is emphysema
a condition where the alveoli of the lungs become inflamed and lose their natural elasticity. they love expand and lose their ability to fill/ contract properly. as air fills up in these sacs, some rupture and become one sack reduce SA for gas exchange. when you breath out, the trapped air cannot be released and breathing becomes more difficult
what asthma
an episodic increase in airway obstruction caused by various stimuli resulting in increased airway resistance. it is reversible. inflammation and bronchoconstriction. airways are sensitive- become irritated, inflamed and narrow= reduce airflow
symptoms of asthma
breathlessness, wheeze, tightness of chest
why is asthma classed as COPD
often reversible in airway disease but can become chronic with some fixed airway damage therefore comes under COPD umbrella
causes of COPD
cigarette smoking (90%)- significant history 20 pack years or more (number of packs per day*number of Yeats smoking), occupational exposure- coal miners, alpha-1 antitryspin deficiency, social deprivation
diagnosis of COPD
detailed patient history. clinical signs- breathlessness on exertion, cough, increased sputum, risk factors, rule out other cases
spirometry- diagnose, categorise severity, monitor progression
CXR
classification- early
often few symptoms, morning cough, chest infections in winter, breathlessness when exercising vigorously. clinical examination may be normal although spirometry may be reduced
classification- moderate
range of respiratory symptoms. cough, wheeze, SOB with moderate exertion, clinical examination may reveal wheeze, barrel chest, flattened diaphragm on CXR
classification- severe
cyanosis, weight loss, raised JVP, peripheral oedema