control of respiration Flashcards

1
Q

Respiration is under automatic control via centers in the ______ and under voluntary control via the _________

A

Respiration is under automatic control via centers in the medulla and under voluntary control via the cerebral cortex

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2
Q

DRG contains primarily

A

inspiratory neurons

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3
Q

ramp signal

A

initial weak AP but gradually increases in amplitude every 6 sec

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4
Q

neurons to the DRG connect to

A

inspiratory muscles by the phrenic nerve and the external intercostal by thoracic spinal nerve

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5
Q

DRG receive input from

A

peripheral cardiopulmonary sensorts

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6
Q

Botzinger complex actas as a _____ and it is found

A

acts as a pacemaker (generated respiratory rhythm) and it is located in the upper part of the VRG

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7
Q

lower part of VRG contains both

A

inspiratory and expiratory neurons

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8
Q

VRG increase the diameted of ______ during inspiration

A

upper airways

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9
Q

caudal region of the VRG sends output of the

A

expiratory muscles (internal intercostals and abdomonal muscles)

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10
Q

how long is resting breathing

A

around 3 sec

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11
Q

when are expiraotyr neurons in the VRG are needed

A

during exercise

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12
Q

the inspiratory and expiratory neurons in the medulla exhibit

A

reciprocal inhibition

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13
Q

The apneustic center, located in the_______ just above the medulla, may exhibit an ______ affect on the DRG and VRG and prolong the ramp action potentials.

A

The apneustic center, located in the lower pons just above the medulla, may exhibit an excitatory affect on the DRG and VRG and prolong the ramp action potentials.

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14
Q

pneumotaxic center is located in the _____ and appears to

A

located in the upper pons and appears to “switch-off” inspiration and thus may regulate inspiratory volume

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15
Q

can cortical centers override functions?

A

yep, it can control breathing

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16
Q

carotid and aortic bodies respond to changes in

A

PaO2, PaCO2 and pH

chemoreceptors

17
Q

how to the signals from carotid an aortic bodies sreach the DRG

A

nerves IX and X

18
Q

Glomus cells are

A

chemosensors

19
Q

which body is more sensitive to hypoxia

A

carotid more than the aortic

20
Q

Higher PaCO2 actually depresses ventilation and leads to CO2 narcosis.

A

true

21
Q

will a decrease in PaO2 results in a more sensitive response of chemosensors when combined with a rise in PaCO2

A

yepppppp, it would lead to a greater stimulation to ventilation

22
Q

The response of chemo-receptors to both increased PaCO2 and decreased PaO2 is enhanced at ______ pH.

A

lower

23
Q

central chemoreceptors are located ________ and provide sensory input to the _____

A

located in the medulla and provide sensory input to the DRG

24
Q

dentral chemoreceptors are stimulated by changes in the

A

pH of the CSF

25
Q

how does H+ diffuse through blood-brain barrier

A

as CO2

26
Q

Hering-Breuer reflex

A

overinflation of the lung sends signals via the vagus nerve to the pneumotaxic center to terminate inspiration

27
Q

slowly adapting stretch receptors

A

mechanoreceptos located within the tracheobronchial tree that fire when the lung volume increases

28
Q

apneustic breathing

A

deep and prolonged inspiration

29
Q

rapidly adapting stretch receptor occur in the

A

upper airways

30
Q

sneeze reflex receptors located in the ______ and respond to

A

nasal mucosa and pharynx and respond to distension of the tissue and irritation

31
Q

cough receptors located in

A

larynx, trachea and bronchi

32
Q

sneeze and cough are caused by

A

irritants

33
Q

irritant receptors ______ respiratory centers to augment respiratory activity and to _____ airways to promote ________ breathing to limit penetration of the noxious agents.

A

irritant receptors stimulate respiratory centers to augment respiratory activity and to constrict airways to promote rapid, shallow breathing to limit penetration of the noxious agents.

34
Q

J receptors respond to

A

J receptors respond to interstitial edema and engorgement of pulmonary capillaries.

35
Q

when J receptors are stimulated the y

A

mediate closure of the larynx and tachypnea in response to pulm. embolism

36
Q

chest wall mechanoreceptors detect

A

impediments to breathing and stimulate inspiratory activity

37
Q

input from the cortex are absolute when it comes to breathing

A

nope; ventilatory drive from chemoreceptors are too strong