Control of Cell Differentiation Flashcards
1
Q
What is the cell phenotype dictated by
A
Constituent proteins
2
Q
What are the stages of cell specialisation
A
Stem cells = Pluripotent
Progenitors = Multipotent
Terminally differentiated cell = unipotent
3
Q
What does the cell need before genes are switched on
A
A number of transcription factors
4
Q
What does a cell need before it can expand and differentiate
A
Extracellular signals
Eg. Low O2 in proximal tubule (EPO receptor gets signal)
Bone marrow is stimulated to produce more RBC progenitor