contraception and sterilization Flashcards
what is the method failure rate vs the typical failure rate surrounding contraceptives
- method failure- the rate that the method is going to fail when used correctly
- typical failure - the rate the method is going to fail when it is used by the patient
what ar the two general mechanisms of contraception?
inhibit formation and release of the egg
create a berrier between the sperm and the egg
what goes into choosing a birth control
efficacy
safety
availability
cost
accebtility
_ contraceptives provide the most reversible contraception
hormonal
oral contraceptives: the combination pill- what is the role of estrogen and progesterone
estrogen: improves cycle control by stabilizing the endometrium and decreases breakthrough bleeding
progesterone: the major player in suppressing LH (which stops ovulation and increases cervical mucuous thickening) which inhbitis sperm migration nad creates an unfavorable atropic endometrium for implantation
suppresses FH and LSH
oral contraceptive: combination pill are phasic formulas meaning they can ?
monophasic or triphasic (mimic the natural cycle)
class combinatino pills is _ days of active hormones and _ days of placebo
21 days
7 days
oral contraceptives: progestin only (mini pill) MOA
makes cervical mucus thick and impermeable
ovulation continues in 40% of users
the mini pill is mainly used in _ women who have contraindication to _
breastfeeding
estrogen
because of the mini pill ow does they must?
be taken at the same time every day
what are some benefits of oral contraceptives
mestrual cycle regularity
stop painful periods
decrease risk of anemia
lowe incidence of endometrial/ ovarian cancers/benign breast/ovarian diseases
what are some side effects of oral contraceptives
breakthrough bleeding, amenorrhea, bloating, breast tenderness, fatigue.
what are some SERIOUS side effects of oral contraceptives?
venous thrombosis
pulmonary embolism
cholestasis anf gall bladder disease
hepatic tumors
stroke/MI
the transdermal patch has _ and _
estrogen and progesterone
how does the transdermal patch work
apply one patch weekly for 3 weeks at a time to dry skin (just not on breast)
is it cautioned in people greater than 198 pounds
transdermal patch has the same side effects as oral contraceptives expect they are at a greater risk for?
thrombosis
brand names for transdermal patches
twirla
ortho evra
the vaginal ring is a combination of _ and _
estrogen and progesterone
the vaginal ring is associated with greater _ becuase of its once a month use- insert into the vagina for up to 3 weeks
compliance
the vaginal ring can be removed for up to _ hours without affecting efficay
3
better tolerated because there is not first pass through the liver
what is the annovera vaginal ring
it is a newer vaginal ring that is has a prescription for 13 months
you use the same ring, place in vagina for 21 days, take out for 7, wash and put back inside
combination product
who cant use combination contraceptives?
women over 35 who smoke cigarettes
people with a history of thromboembolic event/DVT/PE
migranine with auras, uncontrolled hypertension, CAD
liver disease or liver tumors
what is the depot medoxyprogesterone acetate (DEPO Provera)
this is a progesterone only intramusclar shot that is given every 11-13 weeks
depo prevera shot maintains contraceptive level of progestin for about _ weeks
14
what is the MOA of depo provera
thickens cervical mucus, decidualization of the endometrium and blacks LH surge/ovulation
depo provera efficacy is roughly equivalent to that of _ steralization and is not altered by _
sterilization
weight
what is the concern behind bone density and depo provera
it alters bone metabolism because of decreased estrogen
this is concerning in adolescents who are still growing
if you discontinue depot provera the bone symptoms will improve
BBW that you should use for only 2 years
side effects of Depo provera
irregular bleeding (can become amenorrheic after 2 years)
- this can improve if you have estrogen addback
menses will take up to a year to regulate after discontinuation of the medication
weight gain- progesterone makes you hungry
depression exacerbation
what are some reasons why people get on depo provera
contraception
method with good compliance
breastfeeding
when estrogen is contraindicateed
seizures, sickle sell anemia, endometriosis, decrease risk of endometrial hyperplasia