Constipation / Diarrhoea / IBD Flashcards

1
Q

What is acute - intermediate diarrhoea

A

<1 week or <3 weeks

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2
Q

What is chronic

A

> 3 weeks

Always investigate

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3
Q

What causes acute

A

Gastroenteritis = most common
Intussception
NEC

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4
Q

What causes chronic

A
CMPI
Toddler
Coeliac
IBD
Lactose intolerance
Post gastritis lactose intolerance
Pancreatic disease - CF / Schwan
Hyperthyroid 
IBS
Obstruction
Constipation + overflow
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5
Q

What is the mechanism behind diarrhoea

A

Active secretion e.g. infection
Osmotic diarrhoea e.g. malabsorption
Motility disorder = toddler / IBS / constipation

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6
Q

What is toddler’s diarrhoea

A

Common cause
Stools vary and contain undigested food
Child well

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7
Q

What does nocturnal defection suggest

A

Organic pathology

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8
Q

What is important if child has diarrhoea

A

Height and weight

Dehydration

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9
Q

What is secretory diarrhoea and what causes

A

Large volume due to toxin production - Cl via CFTR
Infection
Gastroenteritis
IBD

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10
Q

What is osmotic and what causes

A
Small volume
Large osmotic gap and water moves to equilibrate
Malabsorption
Pancreatic - CF
Hepatobiliary 
Allergy
Coeliac
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11
Q

How do you Rx osmotic

A

Stops when remove offending agent

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12
Q

How do you differentiate

A

Stop trigger in osmotic
Osmotic = large osmotic gap and small vol
Secretory = high electroyte and pH

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13
Q

What is Schwaman Diamond

A

Pancreatic and bone marrow dysfunction

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14
Q

What is most common cause of gastroenteritis

A

Rotavirus

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15
Q

What are other causes of gastroenteritis

A
Adenovirus
Enterovirus
Norovirus
E.coli 
Cambylobacter
Shigella 
Salmonella 
Giardiasis
Amoebiasis
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16
Q

What should you beware of / have to report

A

E.coli 0157

Cholera

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17
Q

What is Ddx

A
Sepsis
Local infection - UTI 
Surgical causes 
DKA
All causes of diarrhoea 
Obstruction if no fever
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18
Q

How does gastroenteritis present

A

Diarrhoea 5-7 days and resolves 2 week
Vomit 1-2 days and resolves 3 day
Fever

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19
Q

Cambylobacter

A

Bloody
Very high fever
Red flags

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20
Q

What are red flags

A
High fever
Tachypnoea
Altered consciousness
Stiff neck
Bloody stool
Bile vomit 
Severe abdo pain or distension
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21
Q

What increases risk of dehydration

A
<1 
LBW 
>6 stools 24 hours
>3 vomit 24 hours
Malnutrition
Not tolerating fluid
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22
Q

Hx

A
Food
Travel
Contact
Sexual
Medication
Bowel
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23
Q

How do you Dx

A

Clinical if well

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24
Q

When do you do stool culture

A
Red flag
Septicaemia
Blood / mucous
Immunocompromised
Foreign travel
\+7 days 
Uncertain
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25
What are complications
``` Dehydration = common Electrolyte imbalance - Hypokalaemia Paralytic ileus Transient lactose intolerance IBS Ketoacdisois if persistent ```
26
Moderate signs of dehydration
Unwell / lethargic Decreased urine Pale Cold
27
What are signs of shock
``` Decreased consciousness Sunken eyes Dry membrane Decreased fontanelle Decreased turgur Tachycardia Weak pulses Prolonged CRT Hypotension ```
28
How do you treat
Fluid replacement Oral if no dehydration ORS (diorite) - 50ml /kg 4 hourly IV if shock - 4,2,1
29
What do you do once rehydrated
ORS every watery stool
30
What are signs of hypernatraemic dehydration
``` Increase tone Hyper-reflexia Convulsion Drowsy Coma ```
31
How do you treat
Isotonic to rehydrate over 48 hours | Decrease Na <0.5mol / l /hour
32
DDX of coeliac in children
CMPI GORD Intolerance Iron deficiency anaemia
33
What is constipation and other symptoms
``` <3 stools per week Hard and large or Rabbit dropping Large stool in rectum or palpable per abdomen Overflow soil >1 episode ``` ``` Other Sx Distress on passing = constipation or ano-rectal Rectal bleeding Poor appetite / pain - improves when pass Abdo distension Irritable Lack of energy Withholding behaviour ``` Can present like appendicitis
34
What are idiopathic causes of constipation / RF
Idiopathic = most common Low fibre Dehydration Excessive milk ``` RF Diet Withholding stool Change to daily routine Not enough exercise FH ```
35
What are other causes
``` Intercurrent illness Spinal cord lesion = always do LL neurology Opiates Hypothyroid Hypercalcaemia Hirschprung Meconium ileus Imperforate anus Obstruction Anal stenosis Gut atresia CMPI Coaliec IBD Sexual abuse ```
36
What is physiological cause
``` Constipation Hard / large stool Followed by pain when passing Avoidance / fear Child withholds Leads to fissure Megarectum -> soiling as sphincter open UTI ```
37
What are RED FLAGS
``` From birth - no stool >48 hours Occur in first few weeks after birth Ribbon stool - anal stenosis Faltering growth / FTT Neuro signs e.g. leg weakness Motor delay Acute, severe abdominal pain + vomting Distension No associated with diet change ```
38
What are symptoms of faecal impaction
Severe constipation Mass Overflow
39
How do you Dx constipation / impaction
Abdominal exam + anus Weight + height LL neurology / spine for dimples - spina bifida X-Ray
40
What is important in Hx
``` How often How hard Previous episode Fissure / painful movement PR bleed Soiling? Withholding behaviour Toilet training Diet / appetite Daily activity Any worries Medication Rx tried Development ```
41
How do you treat 1st line
``` Increased fluid and fibre Decrease milk Toilet = pleasant Regular toilet Reward good behaviour Pharmacologicla = 2nd line ```
42
What is pharmacological Rx
Movicol (isotonic) = 1st line Senna (stimulant) = after 2 weeks if stool now soft Lactulose (osmotic) = if stool hard - Not useful as need to drink loads and children don't
43
What do you do after
Continue laxatives for several weeks then decrease dose
44
When is constipation unusual
Breast feeding
45
What is rare in children
Haemorrhoids
46
What is IBD in children
More severe | More extensive
47
What is important
Maintaining growth
48
U.C
Proctitis rare | Pancolitis common
49
Chron's
Malabsorption - b12 may be only Sx | Upper GI / pan enteric more common
50
What are biochemical disturbances
``` Raised ESR / CRP Anaemia Thrombocytosis Leucocytosis Low albumin ```
51
How do you Dx
``` Exclude infection FBC, U+E, CRP, LFT Blood and stool culture Coeliac -ve Thyroid -ve Raised calprotectin Endoscopy MRI / barium meal if inconclusive ```
52
What is gold standard test
Endoscopy
53
How do you treat
``` Nutrition - supplement FODMAP Elemental feeding = 85% remission and healing Anti-inflammatory Immune suppression Biologics Steroids = last ditch ```
54
What immune suppression
Azathioprine - not in UC Methotrexate Cyclosporin
55
Biologic
Infliximab (anti-TNFa)
56
What is impotant
Maintain growth and development
57
When do you do surgery
Poor growth No puberty Unresponsive to medical Rx
58
What are consequences
``` Poor growth / puberty Colon cancer Haemorrhage Electrolyte Toxic dilatation and megacolon Obstruction Perforation ```
59
What are SE of steroid
``` Infection Weight gain Appetite Moon face Adrenal gland failure Poor growth ```
60
If failure to pass stool first 72 hours
Hirshprung CF - meconium ileus Imperforate anus
61
Constipation + FTT
Coeliac IBD CF Hypothyroid