Asthma Flashcards
What is asthma
Chronic type 1 hyper-responsiveness of airway
Leading to inflammation and obstruction
Inflammation - mucous / muscle hypertrophy and contraction
Variable - 20% peak flow
Reversible - bronchodilator
Responds to treatment
What are types of onset of asthma
Infant Childhood Adult Exertional Occupational
What causes asthma
Genetics FH atopic tendency Atopy - hay fever / eczema / allergy Occupation - smoke LBW Obesity Environment - smoke / pollution
What triggers asthma
Cold air Exercise Smoke Allergen Virus - URTI
How does asthma present
Wheeze SOB - trapped Dry nocturnal exertional cough Diurnal - typically worse at night Tight chest as muscles contract Worse at night
What are signs of asthma
Hypercapnia Hypoxia Cyanosis Tachycardia Accessory muscle Resp distress Hyperinflated lungs Clubbing - chronic hypoxia
When is it NOT asthma
<18 months = VIW Productive cough Stridor (hard inspiratory) Asymmetrical signs / unilateral Dull percussion Crepitations No response to RX
How do you Dx asthma
No investigation in children
What can you do to aid Dx
Trial of ICS
LTRA <5
How do you monitor
Peak flow if >5
If child comes into hospital what tests do you do
Pulse oximetry
Peak flow if >5
ABG if life threatening but VBG will work
Bloods - FBC, U+E as salbutamol = hypoK, lactate+CRP if think sepsis
CXR if suspect pneumonia / pneumothorax
Why is normal CO2 worrying
Hyperventilating so should be low
What are goals of Rx
Minimal Sx
Minimal reliever
No attacks
No limitations
How do you measure control
SABA / week
Absence from school
Nocturnal Sx / week
Exertional Sx / week
What are general measures
Remove trigger
Stop tobacco exposure
What do you do if asthma Dx / suspected
SABA as required
When do you step up
If SABA
>3 week
Nocturnal
Oral steroid
What do you add
8 week trial of Low dose ICS (even if <5 according to NICE)
If Sx resolved but came back after stopped ICS = offer low dose ICS + SABA
If Sx did not resolve consider other Dx
LTRA <5
What do you do if still not controlled
Add LTRA if not controlled after 4-8 weeks Stop if one hasn't worked REFER Add LABA to ICS Increase to medium dose if inadequate Add MART
What are additional
REFER High dose ICS Theophylline Daily steroid Biologics
If still not responding what should you query / before you add on therapies
Inhaler technique Dry CI <8 MDI with spare = gold Psychological Compliance Dx