Connective Tissue (Fibrous) Flashcards
Connective tissue is classified into major groups Embryonic CT and Adult CT. Embryonic CT contains pluripotent stem cells while adult CT is further broken up into what 2 subdivisions?
Include the components of the subdivisions of Adult CT.
Fibrous CT
- Loose Areolar CT
- Dense Regular CT
- Dense Irregular CT
Special CT
- Adipose
- Bone
- Cartilage
- Hematopoietic
All of the following are functions of CT, which of them is specific to adipose tissue?
A. Protection
B. Transport
C. Energy Storage
D. Defense
Energy Storage
Produce collagens, proteoglycans, and glycoproteins.
A. Fibroblasts
B. Mesenchymal cells
B. Adipocytes
D. Chondrocytes
Fibroblasts
Store and release fat cells
A. Fibroblasts
B. Mesenchymal cells
B. Adipocytes
D. Chondrocytes
Adipocytes
Produce and maintain cartilage components
A. Fibroblasts
B. Mesenchymal cells
B. Adipocytes
D. Chondrocytes
Chondrocytes
Which of the following types of fibrous components is known for resisting tension?
A. Elastin fibers
B. Reticular fibers
C. Collagens
Collagens
Which of the following forms a supportive meshwork?
A. Elastin fibers
B. Reticular fibers
C. Collagens
Reticular fibers
Elastin is a stretchable fiber that is an assembly of what 4 components?
Tropoelastin
Fibulin-1
Fibrilins 1
Fibrilins 2
Which type of collagen is the most common and increases tensile strength of CT by being aligned and cross-linked?
A. Type I
B. Type II
C. Type III
D. Type IV
Type I
Which of the following is the characterized of abnormal collagen synthesis leading to weak collagen fibers?
A. Scurvy
B. Ehlers-Danlos Syndrome
C. Marfans syndrome
Ehlers-Danlos Syndrome
NOTE:
Scurvy: Vitamin C deficiency –> cofactor needed for crosslinking collagen
Marfan’s Syndrome: Mutatioon in fibrilin-i gene of elastic fibers causing elastin to be weak
What are the 3 basic fibers found in the extracellular matric of fibrous CT?
Reticular
Elastin
Collagen
What are ground substances, and what role do they serve?
Ground substances: Proteoglycans, Hyaluronan, Glycoproteins, Extracell proenzymes
Combine to form an amorphous framwork structure that allows for shock absorption
Where can embryonic CT be found? What’s another name for this embryonic CT?
Umbilical cord
Wharton’s Jelly
What is the function of adult mesenchymal stem cells?
Self renewing, multipotent stem cells that produce differentiating cells specific for a tissue
Include: Fibroblasts, Muscle cells, osteoblasts, chondroblasts, adipocytes
Low density tissue with both fixed and wandering cells
A. Adipose
B. Areolar
C. Reticular
D. Dense irregular
E. Dense Regular
Areolar