Connective Tissue & Fascia - Class 1 Flashcards
where is CT seen
throughout the body
fxns of CT
supports organs and cells
transports nutrients and waste
defends against pathogens
stores fat
repairs damaged tissues
4 types of tissues in body
muscle
nerve
epithelium
connective tissue
muscle
contractile tissue
nerve
electrical activity
epithelium
covers internal and external surfaces
CT
provides structure and functional support
how much of body weight does CT make up
approx 30%
fluid of bone + dense connective tissue contain approx…
15% of the total body water
4 types of CT
connective tissue proper
cartilage
bone
blood
connective tissue is
3 dimensional tissue with
extracellular matrix & cells
cells that manufacture and support CT
extracellular matrix
stuff outside of the cells
gelatinous base - ground substance (GAGs, proteoglycans, glycoproteins and water)
what is the extracellular matric reinforced by
connective tissue fibers
-collagen, elastin, reticulin
what is the extracellular matric made up of
ground substance
CT fibers
ground substance is made up of
visco-elastic gel
griound substance composition
glycosaminoglycans (GAGs)
H2O
proteoglycans and glycoproteins
GAGs
binds water to ground substance
can hold nearly 1000x their weight –> help provide moisture to skin
extracellular matric fxn
nutrition to CT
fluid which provides…
barrier against infection
fluid which provides… –> extracellular matric fxn
critical fiber distance b/w fibers
mobility of connective tissue
CT fibers
collagen
elastin
reticular fibers
collagen
4 types
toughest, strongest fiber of CT
tropocollagen
4 types of collagen
Type 1 - 4
type 1 collagen
loose and dense CT
type 2 collagen
hyaline cartilage
flexibility and support
type 3 collagen
lining of arteries and organs
type 4 collagen
basement membrane
mechanical stability
cellular adhesion and survival
tropocollagen
basic unit of collagen
elastin
has the most extensibility
less strength than collagen/more than reticulin
where is elastin found
skin
lungs
heart
tendons
ligaments
artery linings
ligamentum flavum
reticulin
fine fibers with least strength
supports internal organs
connective tissue cells
fibroblasts
fibrocytes
macrophages
mast cells
plasma cells
fibroblasts
contributes to formation of CT
synthesizes collagen
fibrocytes
mature fibroblasts
macrophages
assist in healing
mast cells
part of immune system
release histamine
plasma cells
antibody for infection
connective tissue proper
named according to fiber concentration/arrangement
types of connective tissue proper
dense regular
dense irregular
loose irregluar
dense regular is also called
fibrous CT
dense regular CT
high concentration of fibers
arranged in a regular pattern
dense regular CT has
high concentration of collagen
high tensile strength in one direction
where is dense regular CT found
tendons and ligs
blood vessel walls
what does regular CT do
supports, protects and holds bones, mm and other tissues and organs in place
dense irregular CT
high conc of fibers/arranged in haphazard fashion
dense irregular CT has
high conc of collagen
with standard forces in various directions
where is dense irregular CT found
dermal layer of skin and aponeuroses
loose irregular connective tissue
low conc of fibers arranged in haphazard fashion
loose irregular CT has
less tensile strength
contains finer elastin fibers and thicker collagen fibers
loose irregular CT resists
forces in various directions
ex of loose irregular connective tissue
a lymph gland and hypodermis
where is loose irregular tissue found
directly beneath the epidermis/papillary layer of the dermis
fxn of CT (2)
diffusion of nutrients
barrier against trauma and infection
allows body to move
“critical fiber distance”
allows body to move
H2O allows tissue to slide on each other
“critical fiber distance”
fluid creates distance b/w fibers so they dont create adhesions within the CT
visco-elastic
viscous and elastic
viscous
gel like so can be stretched
elastic
tends to return to previous length
stretching of connective tissue
as tension increases, collagen fibers arrange in the direction of the tension
fascia
CT envelope that supports the body and gives it shape
what is fascia
thin casing of CT
where is fascia located
under the skin and in deeper locations throughout the body
what does fascia do
holds everything in place
what does fascia contain
nerves
make it almost as sensitive as the skin
what happens when fascia undergoes mechanican stress
“tighten up”