Connective Tissue Disease Flashcards
What type of vascular CT diseases can occur?
Large vessel disease
Medium vessel disease
Small vessel disease
What is the general management for a vascular CT disease?
Analgesic NSAIDS - for joint or muscle symptoms
Immune modulating treatment - methotrexate
Systemic steroids - prednisolone
What is the disease known as having all of the immune connective tissue diseases?
Lupus
What conditions make up lupus?
Rheumatoid arthritis
Sjögren’s syndrome
Mixed connective tissue disease
Raynaud’s phenomenon
Scleroderma
Dental considerations of a patient with lupus?
Chronic anaemia
- oral ulceration
- GA risk
Bleeding tendency
Renal disease
- issue with drugs and LA
increased risk of lichen oral reactions and oral pigmentation
steroids + immunosuppressants
- increased malignancy risk
What is APS? What dental indications are there?
Antiphospholipid antibody syndrome
- recurrent DVT or emboli
- usually on warfarin to stop the thrombi
Never stop the warfarin as risk of thrombi is too great
- unless consulted with physician
What is Sjögren’s syndrome
Inflammatory disease that attacks ducts such as salivary or tear ducts
Causes dry eyes and dry mouth
- caries
- oral disease
Oral implications of Sjögren’s syndrome?
Xerostomia
Dental caries
Oral infection
Denture retention issues
Salivary lymphoma
Sialosis - swelling of gland
What is systemic sclerosis? Some signs?
Elastic tissue replaced by fibrous tissue in body (collagen)
- Raynauds
- internal issues such as loss of elasticity of oesophagus and gut
Dental implications of systemic sclerosis?
Limited elasticity of oral tissues
- narrowed oral opening
- progressively poor oral access
- limited tongue movement
- swallowing issues
- widening of PDL space but no mobility
(Plan treatment 10 years ahead)
What occurs in vasculitic CT diseases?
Inflammation of blood vessel walls causing
- ischaemia
- infarction of tissue
What is giant cell arteritis?
Temporal arteritis - often temporal artery inflammation
- headache and facial pain
- sometimes occlusion of central retinal artery causing blindness
If a child appears with a very red strawberry appearance of the tongue what may they have? Other associated symptoms?
Kawasaki disease
- erythematous mucosa and strawberry tongue
- crusted or cracked tongue / hands and feet
- lymph involvement
Which CT disease most likely to present to dentist? Why? Clinical signs?
Wegeners granulomatosis
Inflammatory condition starting in upper aero-digestive tract
- destruction of hard and soft tissues of face and oral cavity
- spongy red tissue
