Connective Tissue

Question 1

what is the distribution, molecular organization, and origin cells of collagen type I?

Answer 1

distribution: most CT, dermis, tendons, ligaments, bone, dentin, cementum, fibrocartilage, sclera

molecular organization: thick fibers, known as collagenous fibers

cells that synthesize it: fibroblasts, osteoblasts, odontoblasts, cementoblasts

Question 2

what is the distribution, molecular organization, and origin cells of collagen type 2?

Answer 2

distribution: CARTILAGE!

molecular organization: Thin fibrils

cells that synthesize it: Chondroblasts

Question 3

what is the distribution, molecular organization, and origin cells of collagen type 3?

Answer 3

distribution: organs, smooth muscle, blood vessels

molecular organization: thin fibers known as reticular fibers

cell synthesizing: reticular cells, smooth muscle cells

-its like a spiderweb meshwork lymph nodes and spleen, when you need a lot of cells together in a mesh like structure.

Question 4

what is the distribution, molecular organization, and origin cells of collagen type 4?

Answer 4

distribution: basal laminae (layer of ECM secreted by epithelial cells upon which epithelium sits!)

molecular organization: sheetlike lattice

cell synthesizing: epithelium and skeletal muscle

Question 5

what is the distribution, molecular organization, and origin cells of collagen type 7?

Answer 5

distribution: dermis

molecular organization: anchoring fibrils

cell synthesizing: fibroblasts

Question 6

what is the distribution, molecular organization, and origin cells of collagen type 12?

Answer 6

distribution: tendons, ligaments, Periodontal ligament (PDL)

molecular organization: fibril associated collagen

cell synthesizing : Fibroblasts