Connective tissue

Question 1

Connective tissue functions

Answer 1

Primarily structural
-Organ capsules
-tendons
-ligaments
-areolar tissue filling spaces
Phagocytes and plasma cells

Question 2

Connective tissue develops from

Answer 2

Embryonic mesoderm

Question 3

Connective tissue composed of

Answer 3

ECM and connective tissue cells

Question 4

Resident CT cells

Answer 4

Mesenchymal cells
fibroblasts 
Fibrocytes
Reticular cells
Adipocytes

Question 5

Immigrant CT cells

Answer 5

Macrophages
Mast cells
Plasma cells
Leukocytes

Question 6

Mesenchymal cells

Answer 6

Precursors of CT cells
-stem cells for
fibroblast
smooth muscle
endothelial cell differentiation

Question 7

Fibroblasts

Answer 7

Synthesize and secrete the ECM including CT fibers

• Oval euchromatic nucleus
• structural

Question 8

Fibrocyte

Answer 8

inactive

-spindle shaped with more heterochromatic nucleus

Question 9

Reticular cells

Answer 9

Produce reticular fibers
-form netlike stroma of hematopoietic, lymphoid and adipose tissue

Idaho potato

Question 10

White adipose cells/adipocytes

Answer 10

Specialized for lipid storage

-storage-heat

Question 11

Macrophages

Answer 11

from bone marrow precursors
-divide to produce monocytes- move through blood to CT to form macrophages
defense- phagocytosis
trypan blue

Question 12

Mast cells

Answer 12

Basophilic granules
small central nucleus
found around blood vessels
-defense- histamine, hep
fried egg

Question 13

Plasma cells

Answer 13

differentiate from antigen-stimulated B lymphocytes
Primary producers of circulating antibodies
-immunologic
Clock face

Question 14

3 types of connective tissue fibers

Answer 14

Collagen- large
Elastic- medium
Reticular- small

Question 15

Lymphocytes

Answer 15

Immune cells

-immunologic

Question 16

Eosinophil

Answer 16

Phagocytosis

Immunologic

Question 17

Collagen fibers

Answer 17

Type I
Most widespread
-resists tension

Question 18

Elastic fibers

Answer 18

• picro-orcein and resorcin fuchsin stains

- occurs in body where stretching is needed

Question 19

Reticular fibers

Answer 19

Type III
Flexible meshwork
Stains black with silver salt

Question 20

Fibril associated

Answer 20

type XII

binds type II

Question 21

Form network

Answer 21

Type IV

BM meshwork

Question 22

Anchoring fiber

Answer 22

Type VII

Anchors BM to collagen fibers

Question 23

Oxytalan fibers

Answer 23

Elastic fiber
synthesized in the 1st stage of elastic fiber formation
composed of glycoprotein fibrillin

Question 24

Elaunin fibers

Answer 24

Formed as the amorphous protein elastin

-btwn oxytalan fibers

Question 25

mutations in fibrillin gene

Answer 25

Marfan’s syndrome

Question 26

Osteogenesis imperfeta

Answer 26

Single nucleotide change in type I gene produces aortic rupture, fractures

Question 27

Scurvy (vit C deficiency)

Answer 27

Impaired wound healing

Question 28

Ehlers-Danlos type IV

Answer 28

Type III collagen faulty

-aortic and intestinal ruptures

Question 29

Loose connective tissue

Answer 29

Areolar tissue
-more cellular than dense
found interspersed btwn tissues allowing their relative movement

Question 30

Dense connective tissue

Answer 30

Contains collagen fibers
Dense regular
dense irregular

Question 31

Dense regular CT

Answer 31

Has rope like arrangement

-found in tendons/ligaments/cornea

Question 32

Dense irregular CT

Answer 32

Fabric-like arrangement

-forms most organ capsules/periosteum/dermis of the skin

Question 33

Unilocular Adipose tissue

Answer 33

Yellow/white
composed of cells with a single large droplet of fat
-beneath skin/in/around organs
Develops from undifferentiated mesenchymal cells via lipoblasts

Question 34

Multilocular adipose tissue

Answer 34

brown
Many lipid droplets/cell with abundant mito
primarily in fetus
develops from undifferentiated mesenchymal cells via lipoblasts