Connective tissue Flashcards

1
Q

What are the characteristics of connective tissue?

A

Physically connects other tissues and cells to form organs
Binding material
Metabolic support
Highly vascular
Rich in nerve plexus and lymph vessels

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2
Q

What are the extracellular elements of connective tissue?

A

Ground substance of GAGs, proteoglycans, and glycoproteins

Collagen
Elastin
Reticular

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3
Q

What is the purpose ground substance?

A

Diffusion of small molecules
Lubrication
Barrier to microorganisms

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4
Q

What are the characteristics of collagen?

A

Wavy collagen fibrils bundled
Synthesized by fibroblasts
Resistant to shearing and tearing forces

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5
Q

What are the characteristics of reticular fibers?

A

Collagen type III
Extensive support network
Keep cells in position

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6
Q

What are the characteristics of elastic fibers?

A

Branching pattern
Interwoven with collagen
Elastin core surrounded by fibrillin
Random coiling

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7
Q

Where do we see elastic fibers?

A

Sheets in aorta

Bundles in skin, lungs, uterus, vertebral column, neck

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8
Q

What are the two classifications of connective tissue cells?

A

Resident cells
Wandering/transient cells

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9
Q

What are the resident cells?

A

Fibroblast
Adipocytes
Macrophages
Mast cells
Stem cells

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10
Q

What are the wandering cells?

A

Lymphocytes
Neutrophils
Eosinophils
Basophils
Monocytes
Plasma cells

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11
Q

What are the characteristics of fibroblasts?

A

Principle cells
Synthesis of EC elements
Elongated nucleus

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12
Q

What are the characteristics of mast cells?

A

Develop in bone marrow
Store mediators of inflammation (histamine and heparin)

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13
Q

What are the characteristics of macrophages?

A

Derived from monocytes
Abundant in lysosomes

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14
Q

What are three classifications of connective tissue?

A

Embryonic
Proper
Specialized

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15
Q

What are the two types of embryonic CT?

A

Mesenchymal
Mucoid

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16
Q

What are the two types of CT proper?

A

Loose
Dense

17
Q

What are the two types of dense CT?

A

Regular
Irregular

18
Q

What are the types of specialized CT?

A

Bone
Cartilage
Blood and hemopoietic
Lymphatics
Adipose

19
Q

What are the characteristics of loose connective tissue?

A

Ground substance with scant fibers
Surrounds glands, blood vessels, and beneath epithelia

20
Q

What are the characteristics of irregular dense CT?

A

Few cells, random spreading of collagen fibers, less ground substance
Protects and supports organs
Resists stretching and distension

21
Q

What are the characteristics of regular dense CT?

A

Parallel arrays of collagen fibers with few fibroblasts and little ground substance
Tendons, ligaments, aponeuroses