Connctive Tissue Flashcards

1
Q

Give four examples of connective tissue

A

• Blood

• Cartilage

• Subcutaneous fat

• Bone

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2
Q

What are the functions of connective tissue?

A

• Bind and support other tissues

• Protect and insulate organs

• Transport nutrients

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3
Q

What is the matrix made up of?

A

• Ground substance

• Collagen fibres and elastic fibres (embedded in the ground substance)

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4
Q

What are the two main types of cells found in connective tissue?

A

• Immature class of cell (-blast)

• Mature class of cell (-cyte)

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5
Q

What is the function of the immature cells?

A

Secreting the matrix

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6
Q

What is the function of the mature cells?

A

Maintaining the matrix

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7
Q

What is the ground substance made of?

A

Proteoglycans (a core protein chain) and a polysaccharide side-chain (glucosaminoglycans)

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8
Q

What is the purpose of ground substance?

A

• Support cells

• Bind cells together

• Medium for substance exchange between blood and cells

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9
Q

What are the properties of elastic fibres?

A

• Flexible

• Consists of protein (elastin)

• Can be stretched to 150% of relaxed length without breaking

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10
Q

What are the properties of collagen fibres?

A

• Strong

• Consists of protein (collagen)

• Very tough and resistant to tension forces

• Often arranged in bundles

• Still allows some flexibility because not taut

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11
Q

What are the three types of cartilage?

A

• Hyaline cartilage

• Fibrocartilage

• Elastic cartilage

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12
Q

What are the functions of hyaline cartilage?

A

• Covers articulate surfaces at joints

• Reduces friction between bones

• Absorbs shock

• Has resilient gel and fine collagen fibres

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13
Q

What are the functions of fibrocartilage?

A

• Forms discs and rings between joints

• Great strength and some elasticity

• Can resist considerable pressure

• Bundles of thick collagen fibres

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14
Q

What are the three types of dense connective tissue?

A

• Dense regular CT

• Dense irregular CT

• Elastic CT

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15
Q

What two structures are examples of dense regular CT?

A

Ligaments and tendons

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16
Q

What are the properties of dense irregular CT?

A

• Provides strength in multiple directions

• Collagen fibres randomly arranged

• A few elastic fibres

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17
Q

What is the difference between dense regular and dense irregular CT?

A

Dense regular CT has collagen fibres running in parallel bundles whereas dense irregular CT has collagen fibres randomly arranged

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18
Q

Give two examples of dense irregular CT

A

• Joint capsule

• Deep fascia

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19
Q

What are bones (osseous tissue) made of?

A

Collagen and hard minerals (e.g. calcium, magnesium and phosphate)

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20
Q

What are the two types of bone?

A

• Cancellous or spongy

• Compact

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21
Q

What are the three types of bone cells?

A

• Osteoblasts

• Osteoclasts

• Osteocytes

22
Q

What is the function of osteoblasts?

A

• Deposit inorganic salts and osteoid in bone tissue

• Creating bone

23
Q

What is the function of osteoclasts?

A

• Breaking down bone to release calcium and phosphate

• Involved in maintaining bone shape during growth and removing excess callus formed during healing

24
Q

What is the function of osteocytes?

A

• Monitor and maintain bone tissue

• Communicate with surface osteoblasts and osteoclasts in response to strain

25
Describe the microstructure of compact bone
• Outer layer is called periosteum • Contains osteons which are parallel tube shaped structures containing blood vessels and nerves (within the central/Haversian canal) ◦ Aligned the same way force is applied to the bone • Each central canal is linked to other canals via perforating canals • Lamellae are located around the osteons • Between adjacent lamellae of the osteon are little cavities called lacunae ◦ Within each lacuna is an osteocyte
26
Describe the microstructure of spongy bone
• Spongy bone has a less compact structure (resembling honeycomb) • Contains osteocytes within lacunae but not arranged in concentric circles • Consists of trabeculae which are lamellae that are arranged as rods or plates • Spaces in between contain red bone marrow (which produces blood cells)
27
What do irregular, long and short bones develop from?
Rods of cartilage (cartilage models)
28
What do sesamoid bones develop from?
Tender models
29
What do flat bones develop from?
Membrane models
30
Describe the process of osteogenesis in long bones
• Osteoblasts secrete osteoid which gradually replaces the cartilage model • Calcium and phosphate salts are deposited through the cartilaginous osteoid and increasingly calcify the cartilage model • Ossification begins at the ossification centre • At around 8 weeks, you get the development of a bone collar • The blood supply then starts to develop and bone tissue replaces cartilage as the osteoblasts secrete osteoid into the shaft of the long bone • Ossification continues and spreads to the epiphyses, resulting in bone lengthening • At the time of birth, the secondary centres of ossification develop in the epiphyses and the medullary canal/cavity forms by the osteoclasts breaking down bone tissue in the centre of the shaft • The long bones continue to grow during childhood (which occurs at the growth/epiphyseal plate) and the plate produces new cartilage on the surface which is then converted into bone (lengthening the bone) • During puberty, cartilage growth slows down (meaning there’s more bone deposition in the epiphyseal plate) • This causes the whole plate to be gradually converted into bone over time so no more lengthening is possible
31
What does Wolff’s law state?
Bone density changes in response to the forces placed on the bone
32
What percent of bone is replaced each year?
Around 10%
33
What are the three functional classifications of joints?
• Synarthroses (immovable e.g. joints between bones in the skull) • Amphiarthroses (slightly moveable e.g. joints between adjacent vertebrae) • Diarthroses (freely moveable e.g. knee joint)
34
What are the three groups that diarthroses joints can be split into?
• Uniaxial (movement in one plane) • Biaxial (movement in two planes) • Multiaxial (movement in three planes)
35
What are the three main structural classifications of joints?
• Fibrous • Cartilaginous • Synovial
36
How many types of fibrous joints are there?
3
37
What are the types of fibrous joints?
• Sutures • Gomphosis • Syndesmosis
38
What are the properties of suture joints?
• Permits no movement (only found where bones of the skull meet each other) • Bone edges are serrated and are united by a layer of fibrous tissue • Periosteal layers of the bone are continuous
39
What are the properties of gomphosis joints?
• A peg fits into a socket and is held in place by a fibrous band or ligament • E.g. where roots of teeth are held in their socket by dontal ligaments
40
What are the properties of syndesmosis joints?
• United by a larger amount of fibrous tissue via a ligament or an interosseous membrane (e.g. between radius and ulna) • Movement allowed is due to the flexibility of the membrane or stretching of the ligament • Movement is quite restricted and controlled
41
How many types of cartilaginous joints are there?
Two
42
What are the two types of cartilaginous joints?
• Synchondroses • Symphysis
43
What are the properties of synchondroses joints?
• Bones are untied by a continuous layer of hyaline cartilage • Temporary • Only example of this joint in adults is the first sternocostal joint • In kids, it can be found at the epiphyseal growth plate
44
What are the properties of symphysis joints?
• Articulating surfaces of the bones involved are covered in hyaline cartilage and also have a pad of fibrocartilage between them (e.g. between vertebrae) • Allows a small amount of controlled movement to take place
45
What are the properties of synovial joints?
• Articulating surfaces of the bones are covered in an articular hyaline cartilage (allowing bones to move against one another with minimal friction) • There is a fibrous joint capsule that attaches at or away from the margins at the joint (strengthened by the muscles and ligaments that cross the joint) • Deep surface of the capsule is lined by the synovial membrane (which secretes synovial fluid into the joint cavity)
46
How many types of synovial joint are there?
Seven
47
What are the types of synovial joint?
• Gliding joint (plane joint) • Hinge joint • Pivot joint • Ellipsoid joint • Saddle joint • Ball and socket joint • Condyloid joint
48
What are the properties of each synovial joint?
◦ Gliding joint (plane joint) ‣ Joint surfaces are relatively flat and are roughly equal length ‣ Some movement is possible by one bone gliding or twisting against the other ‣ E.g. sternoclavicular joint ◦ Hinge joint ‣ Allows movement about one axis only ‣ Good congruency of the joint surfaces (fit each other nicely) ‣ E.g. elbow joint ◦ Pivot joint ‣ Movement occurs at a single axis with one bone rotating around another within a fibro-osseus ring ‣ E.g. joint at the top of the spine where atlas meets axis (Atlanto-axial joint) ◦ Ellipsoid joint ‣ Similar to ball and socket joint but the surfaces are ellipsoid ‣ Movement is only possible about two perpendicular axes ‣ E.g. radio-carpal joint at the wrist ◦ Saddle joint ‣ Two surfaces are reciprocally concavo-convex ‣ Like a rider sitting on a saddle ‣ Allows movement to occur primarily about two perpendicular axes ‣ Usually allows a small amount of movement about a third axis ‣ E.g. Carpo-metacarpal joint of the thumb ◦ Ball and socket joint ‣ Ball of one bone fits into the socket of another bone ‣ Multiaxial joint (capable of movement in multiple planes and at least three axes) ◦ Condyloid ‣ Modified ball and socket joint ‣ Allows active movement about two perpendicular axes ‣ Passive movement could occur about a third axis ‣ E.g. metacarpal-phalangeal joints
49
What is joint arthrokinematics?
The specific movement of joint surfaces
50
What are the three types of movements available at joints?
• Roll, spin and slide/glide