Congenital renal pathoma 12/21 Flashcards
Formation of stones and infections are related with ……… (disease)
Horseshoe kidneys.
Hydronehprosis is associated with …….. (disease)
Horseshoe kidneys.
Oligohydramnios causes pulmonary hypoplasia by mechanism: ……….
Due to the lack of normal alveolar distention by aspirated amniotic fluid.
I. Horsehoe kidney. Which part connected?
lower poles
What congenital is the most common?
Horsehoe kidney.
I. Where is located horsehoe kidney? (abnormal)
abnormally located in the lower abdomen
I. Horsehoe kidney. Under what vessel?
Inferior mesenteric artery
Kidneys got cought by this vessel when it ascents from pelvis to abdomen and get stucked.
II. Renal agenesis. what is it?
Absent kidney formation
II. Renal agenesis. unilateral or bilateral?
may be both
II. Renal agenesis. Unilateral. Leads to what?
Hypertrophy of the existing kidney
II. Renal agenesis. Unilateral. What physio process in other kidney?
Hyperfiltration that increases risk of renal failure later in life.
II. Renal agenesis. Bilateral. Leads to what?
Oligohydramnios
II. Renal agenesis. Bilateral. How is called disease and what manifestation?
Potter sequence.
Oligohydramnios with lung hypoplasia, flat face with low set ears, developmental defects of the extremities.
What diseases is impatible with life?
II. Renal agenesis. Bilateral –> POTTERS SEQUENCE
Potter sequence.
Oligohydramnios with lung hypoplasia, flat face with low set ears, developmental defects of the extremities.?
II. Renal agenesis. Bilateral.
Hyperfiltration that increases risk of renal failure later in life.?
II. Renal agenesis. Unilateral.
Hypertrophy of the existing kidney?
II. Renal agenesis. Unilateral.
III. Dysplastic kidney. Inheritance?
Noninherited
III. Dysplastic kidney. definition?
Congenital malformation of the renal parenchyma
III. Dysplastic kidney. how is characterized morphologically?
Congenital malformation of the renal parenchyma characterized by CYSTS AND ABNORMAL TISSUE (eg cartilage)
III. Dysplastic kidney. which side?
Usually unilateral;
III. Dysplastic kidney. What need to do if bilateral?
must be distinguised from inherited polycystic kidney disease
must be distinguised from inherited polycystic kidney disease?
III. Dysplastic kidney. bilateral
IV. PKD. Inheritance?
Inherited
IV. PKD. what side affected?
bilateral
IV. PKD. Morphology?
Bilateral enlarged kidneys with cysts in renal CORTEX AND MEDULLA
IV. PKD. AR inheritance. what population?
Infants
IV. PKD. AR inheritance. Associated with what?
Congenital hepatic fibrosis –> leads to portal hypertension and hepatic cysts.
IV. PKD. AR inheritance. symptoms?
In infants as worsening renal failure and hypertension. New borns may be present with potters sequence
In infants as worsening renal failure and hypertension. New borns may be present with potters sequence?
IV. PKD. AR inheritance.
Congenital hepatic fibrosis –> leads to portal hypertension and hepatic cysts.?
IV. PKD. AR inheritance.
IV. PKD. AD inheritance. What population?
Young adults
IV. PKD. AD inheritance. Symptoms?
in young adults as hypertension (due to increased renin), hematuria and worsening renal failure.
in young adults as hypertension (due to increased renin), hematuria and worsening renal failure.?
IV. PKD. AD inheritance.
IV. PKD. AD inheritance. mutations?
APKD1 and APKD2 gene.
IV. PKD. AD inheritance. how develops cysts
over time
IV. PKD. AD inheritance. associated with what?
berry aneurysms -> SAH., hepatic cysts, mitral valve prolapse.
berry aneurysms -> SAH., hepatic cysts, mitral valve prolapse?
IV. PKD. AD inheritance.
APKD1 and APKD2 gene?
IV. PKD. AD inheritance.
V. Medullary cystic kidney diseases. Inheritance?
Inherited
V. Medullary cystic kidney diseases. what type of inheritance?
AD
V. Medullary cystic kidney diseases. morphology?
defect leading to cysts in the medullary collecting ducts
V. Medullary cystic kidney diseases. presentation?
parenchymal fibrosis results in shrunken kidney and worsening renal failure.
parenchymal fibrosis results in shrunken kidney and worsening renal failure.?
V. Medullary cystic kidney diseases. (AD)
defect leading to cysts in the medullary collecting ducts?
V. Medullary cystic kidney diseases. (AD)
III. Dysplastic kidney. Unilateral - symptoms?
Asymptomatic
III. Dysplastic kidney. Bilateral - symptoms?
Early, severe renal insufficiency due to absence of functional renal tissue
III. Dysplastic kidney. UW definition of morphology.
Noncommunicating cysts intervening with dysplastic tissue
