Concentration, Time and Dose Flashcards
1
Q
What are the 4 main phases in pharmacokinetics?
A
Absorption
Distribution
Metabolism
Excretion
2
Q
What are the main features of a dose - time - effect graph?
A
AUC // Peak (Cmax) // Slope (absorption and elimination).
3
Q
What is an anti - epileptic drug that is used?
A
Phenytoin = Used in an emergency situation in order to stop epileptic seizures.
4
Q
How is a steady state achieved?
A
A steady infusion is used.
5
Q
What is the definition of a steady state?
A
This is where the administration and elimination of a drug are in equilibrium.
6
Q
What is a loading dose?
A
Dosage given to achieve a therapeutic concentration QUICKLY.
Used when the elimination is SLOW.
