Compendium 5 - moving substances into the cell and ATP synthesis Flashcards
what 3 factors affect whether a substance can diffuse straight into a cell
- solubility in lipids
- size
- is it moving against and along conc. gradient
what are the 3 types of passive transport and what type of molecule would undergo this transport
- diffusion through bilayer - gases, small alcohols, lipids, urea
- diffusion through ion channel - small ions, water,
- facilitated diffusion using a carrier protein - glucose (in) and fructose (out)
what is primary and secondary active transport
primary - energy derived directly from ATP
secondary - using a cotransport (eg. Na+ really wants to get into the cell and it drags glucose with it against glucose’s concentration gradient)
what are the 2 types of secondary active transport
symporters - both travel in same direction
antiporters - travel in opposite directions
what are the 3 types of Endocytosis and what are they each used for
pinocytosis - engulfing small particles and fluids
phagocytosis - engulfing large particles
receptor mediated endocytosis - moving specific substances into the cell, in the caveolae regions (membrane able to form vesicles)
what is the driving force for osmosis
solute concentration - water movement from low solute concentration to high solute concentration
what are the products from ONE glucose molecule at the end of glycolysis
2x pyruvate
4x ATP
2x NADH
what has to happen between glycolysis and the citric acid cycle and what is produced
for the pyruvate to enter the mitochondria it must turn into acetyl Coenzyme A, which produces 1 NADH and 1 CO2 per pyruvate molecule
what are the overall (from both pyruvates) products produced from the citric acid cycle
2x ATP
6x NADH
2x FADH2
how is a proton gradient created and what is it used for
it is produced when electrons are taken from the NADH and FADH2 molecules and given to the proteins in the membrane and the H+ ions that are released are moved into the intermembrane space with the energy produced by the movement of the electrons.
it is used to create a concentration gradient so they can move back into the cell through the ATP synthase protein to produce ATP.
what is the final electron acceptor and what does it produce
O2 finally accepts the electrons and forms water