Compendium 5. Fuelling the Human Body Flashcards
What is the difference between peripheral and integral proteins?
Peripheral - on the edge on the membrane
Intergral - All the way through the membrane
Describe Channel proteins
- Integral
- Only molecules of a certain shape and size can pass through
- Can be gated or non gated
What is the difference between gated ion channels and non gated ion?
Non gated - always open for movement
Gated - Can be opened or closed depending on certain stimuli
Describe Carrier proteins
- Also known as transporters
- Integral
- Have specific binding sites
- The protein will change shape to allow molecules to pass through
- Uniporters, symporters and antiporters
What are uniporters, symporters and antiporter?
Uniporters - (carrier proteins that only transport one molecule)
Symporters - (carrier proteins transports two molecules moving in the same direction)
Antiporters - (carrier proteins that transport two molecules moving in opposite directions across the membrane).
Describe ATP - powered transport
- Requires energy in the form of ATP
- Transports molecules AGAINST their concentration gradient
What are the 4 main functions of the cell membrane?
- Supports and encloses the cell
- Attaches cells to other cells and to the surrounding matrix
- Communicates to the cell’s environment and other cells
- Determines what moves into and out of the cell (selectively permeable)
Define Solute
Dissolved substances in a solution eg glucose, sucrose, ions
Define Solvent
The liquids that hold solutes
Define Solution
The mixture of the solute in the solvent
What is Diffusion?
Molecules moving from areas of high concentration to areas of lower concentration so that they are evenly distributed throughout the solution
How do lipid soluble molecules move across the cell membrane?
They diffuse directly through the cell membrane
How do non-lipid molecules move across the cell membrane?
- Some specific non-soluble molecules can diffuse through membrane channels
- Other molecules for which channels are not present cannot pass through the cell membrane
What is facilitated diffusion?
- The movement of a solute (e.g. glucose) across a plasma membrane via the use of a carrier/channel protein.
- No ATP is used.
What is Osmosis?
The diffusion of water across a selectively permeable membrane from areas of high concentration to areas of low concentration