Colorectal Carcinoma Flashcards
1
Q
Lynch etiology
A
mismatch repair
microsatellite instability
right-sided cancers
+ ovarian and endometrial cancers
2
Q
Adenoma –> carcinoma sequence
vs
microsatellite instability
A
A->C more common, esp in left
microsatellite instability: in right colon
3
Q
CEA
A
track
Tx response
recurrance
in colorectal cancer
4
Q
S. bovis
A
causes endocarditis
gets into blood when tumor invades from colon into blood supply
so if pt has strep bovis endocarditis, need to check for colon tumor
5
Q
Sx of left-sided vs right-sided tumors
A
left: blood in stool
right: iron-deficiency from chronic blood loss
6
Q
Stool in left sided colon carcinoma
A
decreased caliber (ring lesion) possible bleeding
