colorectal cancer Flashcards

1
Q

duke a

A

no serosal fat , only bowell wall
good5 year prognosis

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2
Q

duke a …
survielance follow up?
colonoscopy

A

anually… first 2 yrs
then 3rd yearly

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3
Q

duke a
survey occult blood

A

monthly first 4 yrs
then yearly

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4
Q
A
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5
Q

col ca bowel habits

A

may or may not change

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6
Q

col ca blood work and age ?

A

anaemia + old age

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7
Q

dermoid cyst

A

females of child bearing age
multiple tissues involved

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8
Q

anaemia : do nothing and reassure

A

young age +
anaemia resolvable by supplements

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9
Q

> sixty yrs and anaemia

A

faecal occult blood testing

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10
Q

colonoscopy indication for screening

A

both 1st and 2nd degree
relatives have cancer

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11
Q

col ca rx

A

angiogenesis inhibitor
BEVACIZUMAB( VEGF inhibitor)

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12
Q

co ca rx:
CAPE CITA BANE ?

A

prodrug of 5FLUROURACIL

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13
Q

CAPECITABANE advantage

A

ORAL BD
…. instead of 5fu iv for 24 hrs

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14
Q

COL CA
METASTASIS indication ???

A

high CEA levels

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15
Q

meckels diverticulum see ?

A

technitium scan

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16
Q

col ca METASTASIS RX ??

A

OXALI PLATIN
Multitherapy
with
5fu +folinic acid

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17
Q

> SIXTY yrs plus anaemia
anaemia evaluation

A

COLONoscopy
then
upper gi Endoscopy

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18
Q

COL CA
CEA use ?

A

1=post operative surviellance
2=disease progression
3=diesease free survival rate

19
Q

col ca … plus …?
in presence of LIVER METS
WHAT disease or syndrome

A

carcinoid syndrome
HORMONE excess
RX RESECTION WITH METS , OCTREOTIDE AND peptide receptor RT

20
Q

carcinoid syndrome in COL CA
which hormone ?

A

neuro endocrine tumor
SERITONIN excess in liver mets

21
Q

neuro endocrine tumor m/C location

22
Q

PARAGANGLIOMA

A

neck
catecholamines secrete 2 percent
tumor of sympathetic nervous system

23
Q

pheocromocytoma
secrete

A

adrenaline
loc at adrenal

25
COL CA and other cancer associations ?
endometrial ca hnpcc
26
Endometrial ca in Col ca?
HERIDITORY NON POLYPOSIS COL CA (HNPCC) ONSET 44 YEARS men COL CA 0 percent females col ca 40 percent AND ALSO FEMALES : DEVELOP ENDOMETRIAL CANCER 50 PERCENT HIGH CHANCE
27
COL CA with LIVER mets symptoms
CarCInoiD SYNdrOME SYSTOLIC MURMUR PROXYSM ABDOMEN PAIN DIAHHROEA FLUSHING
28
carcinoid syndrome symptoms rx
octreotide if inaffective
29
octreotide ineffective in CD symtoms rx
CYPRO HEP TADINE METHY SER GIDE
30
Microbial risk for COL CA
STREPtococcus BOVISSS causes endocarditis ,, murmurs
31
COL CA query PLUS MURMURS plus fever
endocarditis by streptococcus bovis
32
strep bovis location
Large bowel
33
m/c cause of endocarditis generally
staph aureas
34
COL ca premalignant lesion ?
SERRATED polyps
35
col ca Bad prognosis not surviellance
depth RIGHT SIDE location( ascending colon) cicumference size
36
m/c location for Col ca
left side decending and sigmoid colon most symptoms
37
rt side co ca
ascending colon bad prognosis less symptoms
38
Col ca DUKE A
Bowell wall NO SEROSA FAT
39
COLCA duke B
SEROSA involves
40
Col CA DUKE C....
LYMPH NODES
41
COL CA DUKE.... DDDD
Distant mets primary to liver
42
oxaliplatin
muti therapy non motor neuropathy only sensory neuropathy
43
oxaliplatin
NEURO and OTO toxic NEUTROPENIA RENAL FUCTION MONITOR in renal impa
44
platinum therapy fail eg cisplatin ,oxaliplatin col ca rx?
IRINOTECAN