colorectal cancer Flashcards

1
Q

duke a

A

no serosal fat , only bowell wall
good5 year prognosis

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2
Q

duke a …
survielance follow up?
colonoscopy

A

anually… first 2 yrs
then 3rd yearly

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3
Q

duke a
survey occult blood

A

monthly first 4 yrs
then yearly

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4
Q
A
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5
Q

col ca bowel habits

A

may or may not change

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6
Q

col ca blood work and age ?

A

anaemia + old age

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7
Q

dermoid cyst

A

females of child bearing age
multiple tissues involved

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8
Q

anaemia : do nothing and reassure

A

young age +
anaemia resolvable by supplements

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9
Q

> sixty yrs and anaemia

A

faecal occult blood testing

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10
Q

colonoscopy indication for screening

A

both 1st and 2nd degree
relatives have cancer

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11
Q

col ca rx

A

angiogenesis inhibitor
BEVACIZUMAB( VEGF inhibitor)

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12
Q

co ca rx:
CAPE CITA BANE ?

A

prodrug of 5FLUROURACIL

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13
Q

CAPECITABANE advantage

A

ORAL BD
…. instead of 5fu iv for 24 hrs

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14
Q

COL CA
METASTASIS indication ???

A

high CEA levels

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15
Q

meckels diverticulum see ?

A

technitium scan

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16
Q

col ca METASTASIS RX ??

A

OXALI PLATIN
Multitherapy
with
5fu +folinic acid

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17
Q

> SIXTY yrs plus anaemia
anaemia evaluation

A

COLONoscopy
then
upper gi Endoscopy

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18
Q

COL CA
CEA use ?

A

1=post operative surviellance
2=disease progression
3=diesease free survival rate

19
Q

col ca … plus …?
in presence of LIVER METS
WHAT disease or syndrome

A

carcinoid syndrome
HORMONE excess
RX RESECTION WITH METS , OCTREOTIDE AND peptide receptor RT

20
Q

carcinoid syndrome in COL CA
which hormone ?

A

neuro endocrine tumor
SERITONIN excess in liver mets

21
Q

neuro endocrine tumor m/C location

22
Q

PARAGANGLIOMA

A

neck
catecholamines secrete 2 percent
tumor of sympathetic nervous system

23
Q

pheocromocytoma
secrete

A

adrenaline
loc at adrenal

25
Q

COL CA and other cancer associations ?

A

endometrial ca
hnpcc

26
Q

Endometrial ca in Col ca?

A

HERIDITORY NON POLYPOSIS COL CA (HNPCC)
ONSET 44 YEARS
men COL CA 0 percent
females col ca 40 percent
AND ALSO
FEMALES : DEVELOP ENDOMETRIAL CANCER 50 PERCENT HIGH CHANCE

27
Q

COL CA with LIVER mets symptoms

A

CarCInoiD SYNdrOME
SYSTOLIC MURMUR
PROXYSM ABDOMEN PAIN
DIAHHROEA
FLUSHING

28
Q

carcinoid syndrome symptoms rx

A

octreotide
if inaffective

29
Q

octreotide ineffective in CD symtoms rx

A

CYPRO HEP TADINE

METHY SER GIDE

30
Q

Microbial risk for COL CA

A

STREPtococcus BOVISSS

causes endocarditis ,, murmurs

31
Q

COL CA query PLUS MURMURS plus fever

A

endocarditis by streptococcus bovis

32
Q

strep bovis location

A

Large bowel

33
Q

m/c cause of endocarditis generally

A

staph aureas

34
Q

COL ca premalignant lesion ?

A

SERRATED polyps

35
Q

col ca Bad prognosis not surviellance

A

depth
RIGHT SIDE location( ascending colon)
cicumference
size

36
Q

m/c location for Col ca

A

left side
decending and sigmoid colon
most symptoms

37
Q

rt side co ca

A

ascending colon
bad prognosis
less symptoms

38
Q

Col ca
DUKE A

A

Bowell wall

NO SEROSA FAT

39
Q

COLCA duke B

A

SEROSA involves

40
Q

Col CA DUKE C….

A

LYMPH NODES

41
Q

COL CA DUKE…. DDDD

A

Distant mets primary to liver

42
Q

oxaliplatin

A

muti therapy
non motor neuropathy
only sensory neuropathy

43
Q

oxaliplatin

A

NEURO and OTO toxic
NEUTROPENIA
RENAL FUCTION MONITOR in renal impa

44
Q

platinum therapy fail eg cisplatin ,oxaliplatin col ca rx?

A

IRINOTECAN