CHRONS DISEASE Flashcards

1
Q

chrons + ileal resection
symptoms

A

watery diarrhoea
due to bile acid malabsorption

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2
Q

chrons + ileal resection
rx

A

CHOLESTYRAMINE
bile acid sequestrant

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3
Q

chrons … no flare =

A

normal calprotectin and inflammatory markers
no abd pain or disturbance

IF FLARE
rx: ORAL STEROIDS

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4
Q

leocaecal chrons vs ilecaecal tb DD

A

RISK FACTORS FOR TB

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5
Q

CHRONS INTESTINAL SYMPTOMS

A

ORAL ULCERS
abd pain
diarrhoea
weight loss also
bloating and nausea particularly after meals
fistulae

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6
Q

chrons EExtra INTESTINAL symptoms

A

itchy eyes ..uvietis …., episcleritis
tender nodules …. erythema nodosum
pyoderma gangrenosom
vasculitis
abnormal liver enzymes
stone …kidney and gall
FEVER
weight loss
small joint poly arthritis
sacroilitius
clubbing

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7
Q

chrons location m/c

A

rt side
rt iliac fossa

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8
Q

chrons * vs Uc

A

mor common in smokers

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9
Q

chrons * vs Uc

A

chrons happens in small bowel also
UC IS A LARGE BOWEL DISEASE

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10
Q

DIL LOOPS OF SMALL BOWEL in scan

A

stricture

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11
Q

chrons * vs coeliac

A

no strictures in coeliac

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12
Q

chrons * vs pancreatitis

A

small bowel obstruction in crons

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13
Q

chrons ..histology

A

transmural thickness
patchy inflammation
skip lesions
non caseating granuloma

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14
Q

ulcerative ‘C’olitis ….histo

A

CRYPTS
distortion, neutophilic distraction and abcesses

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15
Q

chrons* vs uc

A

stricturing present in chrons on endo

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16
Q

uc* vs chrons

A

uc present in only colon

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17
Q

chrons endoscopy

A

assymetry disease
COBBLE STONE
DEEP FISSURES
STRICTUTES

18
Q

CHRONS * VS SMALL BOWEL LYMPHOMA

A

NO STICTURES AND ULCERATIONS IN lymphoma

19
Q

chrons med treatment

A

sulfasalazine

20
Q

sulfasalazine side effects

A

decreareased blood cells individually or
PANCYTOPENIA lead to
bleed bruising, fever sorethroat etc

somatitis parotitis hpersensitivity

21
Q

sulfasalazine caution

A

g six pd , renal and hepatic impairement

22
Q

Pancytopenia causes

A

sulfasalazine
acute leukaemia
hiv , epstein , hepatitis

23
Q

chrons

LARGE* bowel vc small bowell

A

large bowel=
“L”eft side
b’L’eed
no clubbing and vomitting
in large age groups

24
Q

chrons

SMALL* bowel

A

right side
no … bleeding ,clubbing and vomitting .. in small age

25
ulc col* vs chrons
tenesmus in uc
26
chrons more than one relapse in one year requiring steroids rx for maintenace
Azathiprine stop after years
27
azathiprine adverse effect
lymphoma fever ,artralgia ,rash
28
chrons maintenace M/C And others
azathioprine m/c others = sulfasalazine , mesalazine tnf agents : adalimumab, infli xi zu mab
29
chrons + PERIANAL ABCESS
mri to knowextent or ct ot then exam under anaesthesisa
30
chrons big risk facotor
smoking
31
azathioprine pre check
tmpt tmpt deficiency=no med tmpt low =low dose azathioprine
32
azathioprine complications
myelosuppressive abnormal LFT pancreatitis
33
chrons ... early indication for anti TNF therapy
fistulating chrons
34
Sx in chrons
chrons colitis refractory to meds terminal ilium
35
chrons derma compli
pyoderma garenosum
36
pyoderma gangrenosum
purple ulcer bleeding epidermal necrosis ,neutrophil infiltrate rx =anti TNF
37
normal potassium requirement
1mmol /kg/day...... 90 to 120 mmol
38
potassium requrement for GI LOSS eg bowel resection
higher end 120 mmol/day
39
chrons perianal disease
anal tag
40
chrons* abdomen auscultaion vs UC
tender diffuse inflammatory mass... eg in rt iliac fossa no mass in UC