Coagulation And Thrombocytes Flashcards

1
Q

Stages of platelet hematopoiesis?

A

Megakaryoblast, promegakaryocyte, megakaryocyte, platelet

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2
Q

Made of lit pink cytoplasm and distinct purple granules

A

Platelets

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3
Q

Large platelets (immature)

A

Macro platelets

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4
Q

Three main functions of platelets?

A

Clotting, preserve capillary walls, transport substances for clotting, and for constriction and dilation of blood vessels

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5
Q

Are platelets larger or smaller than RBCs?

A

Smaller

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6
Q

Platelets in ______ vary in size, shape and clumping

A

Cats

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7
Q

Platelets in _____ are relatively uniform in size.

A

Dogs

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8
Q

Macro platelets are normal in….

A

Cats

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9
Q

What do macro platelets indicate in dogs?

A

Increased platelet use and a need for increased platelet production

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10
Q

Normal platelet value for dogs.

A

150,000 plts/uL - 450,000 plts/uL

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11
Q

Normal platelet values for cats.

A

200,000 plts/uL- 600,000 plts/uL

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12
Q

Variation in the size of platelets.

A

Pleomorphic

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13
Q

Cannot stop bleeding at this platelet count number.

A

50,000 plts/uL

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14
Q

Increased of platelets.

A

Thrombocytosis

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15
Q

Two causes of Thrombocytosis?

A

Injury/trauma/infection or steroids/splenectomy

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16
Q

Decrease in number of platelets.

A

Thrombocytopenia

17
Q

Three main causes of thrombocytopenia?

A

Hormone disorder, disorders of platelet distribution, vitamin b12 injection

18
Q

Method one of platelet count.

A

Viewing 10 fields, averaging the fields and reporting them.

19
Q

Normal platelet per field?

A

7-10 platelets/hpf

20
Q

Method two ***** of platelet count?

A

Count and record in ten fields, average them, and times by 15,000 = platelets per microliter

21
Q

Cannot accurately count_____ platelets.

A

Clumped

22
Q

Small pinpoint hemorrhages.

A

Pettichia

23
Q

Blotches of hemmorage (usually abdomen)

A

Echymosis

24
Q

Visible bleeding.

A

Frank

25
Q

Hidden bleeding,

A

Occult bleeding

26
Q

Large amounts of blood

A

Profuse bleeding

27
Q

Steps of clotting?

A
  1. Platelets plug, 2. Clotting factors reinforce plug, 3. Fibrin web acts like glue, 4. Other cells reinforce web
28
Q

Extrinsic

A

PT

29
Q

Intrinsic

A

PTT

30
Q

Five sizes/types of platelets?

A

Macro platelets, micro platelets, increased platelets, decreased platelets, clumped platelets

31
Q

Platelets size of a red cell.

A

Macro platelet

32
Q

The glue.

A

Fibrin

33
Q

What do you have to do when you see clumped fibrin?

A

Send the sample out

34
Q

Which organ produces the most clotting factors?

A

Liver