CNS drugs

Question 1

Benztropine

Answer 1

• anticholinergic agent that can be used to treat tremor in Parkinson disease
• counteract the extrapyramidal side effects of neuroleptic medications such as haloperidol.

Question 2

diazepam

Answer 2

long-acting benzodiazepine that positively modulates GABA-A activity.

Question 3

Haloperidol

Answer 3

• antipsychotic that blocks dopamine receptors in the CNS

- commonly used to treat the positive symptoms of psychosis (eg, delusions, hallucinations).

Question 3

lithium

Answer 3

BUN, creatinine, and thyroid function tests should be routinely monitored in patients taking the mood stabilizer due to its potential to cause hypothyroidism and impair renal function

• Lithium toxicity is associated with neuromuscular excitability (irregular coarse tremors, fascicular twitching, rigid motor agitation, and ataxia)
• cause nephrogenic diabetes insipidus, hypothyroidism, and cardiac conduction defects,

Question 4

Cocaine

Answer 4

blocks the re-uptake of norepinephrine, serotonin, and dopamine in the CNS
- can cause cardiac ischemia, hypertension, and seizures. Cocaine withdrawal is associated with severe depression.