CMV and EBV

Question 1

what is different from CMV and herpesvirus

Answer 1

• size of DNA greater

- additional viral messenger RNA

Question 2

what is CID cytomegalic inclusion disease

Answer 2

congenital infection

Question 3

what organs are targeted in CID

Answer 3

visceral organs

Question 4

when and where are newborn infections aquired

Answer 4

last trimester, CMV secreted in cervix

Question 5

how is CMV/CID transported

Answer 5

lympoid system and monocytes

Question 6

in what tirmester can CMV be secreted to cervix

Answer 6

3

Question 7

how do most peoples symptoms present in CMV

Answer 7

asymptomatic

Question 8

what can cause reactivation of latent infection

Answer 8

immunosuppression

Question 9

what proteins are on EBV that attach virus to surface of cell in permissive cells

Answer 9

gp350/220

Question 10

in latent infection of EBV was genes are expressed from circular genome

Answer 10

EB nuclear antigen EBNA

latent proteins

Question 11

in b cell immortalization what proteins are used for other cell interaction

Answer 11

latent membrane proteins

Question 12

what are symptoms if mono presents early age? adolescne or adulthoos

Answer 12

no diease

more severe

Question 13

monospot test

Answer 13

heterophile antibodies –> reacts with horse/sheep RBC

Question 14

what is the best lab test of EBV

Answer 14

virus neutralization

immunofluoresence

Question 15

HHV6B infect what cells? latent infection occurs in?

Answer 15

B and T

T and monocytes

Question 16

what part of the body is HHV6B found

Answer 16

saliva

Question 17

HHV7 symptoms

Answer 17

high fever

rash follows end of fever

Question 18

HHV8

Answer 18

Kaposi sarcome

B cell lymphoma

Question 19

HHV8 do in body

Answer 19

slow down apoptosis