AIDS- Norton Flashcards

1
Q

what cell populations are infected by HIV

A

CD4 T
monocytes
dendritic cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

how does HIV impact intracellular in CD 4 T cells

A

increase plasma membrane permeability

-interferes with cell protein synthesis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

how do uninfected cells get killed in HIV

A
  • activation-induced apoptosis

- pyroptosis by inflammasome pathway

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

what organ is destroyed by HIV

A

lymphoid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly