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Yr 3 - Reproduction > Clinical Pathological Conference of the Uterus > Flashcards

Clinical Pathological Conference of the Uterus Flashcards

1
Q

How is post-menopausal bleeding investigated?

A

Trans-vaginal USS
Endometrial biopsy
Hysteroscopy

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2
Q

What is the use of Trans-vaginal USS?

A

Measure endometrial thickness

Look at endometrial contour

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3
Q

When is Endometrial biopsy indicated?

A

Trans-vaginal USS shows endometrium >4mm or irregular

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4
Q

What are the prognostic indicators for endometrial cancer?

A

Histological type
Histological grade
Stage
Lymphovascular space invasion

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5
Q

How is Endometrial cancer staged?

A

Surgery/pathology

MRI

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6
Q

What can MRI establish in endometrial cancer?

A

Depth of myometrial invasion
Cervical involvement
Lymph node involvement

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7
Q

What stage is endometrial cancer contained to the inner half of myometrium?

A

1A

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8
Q

What stage is endometrial cancer contained to the outer half of myometrium?

A

1B

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9
Q

What stage is endometrial cancer invading the cervix?

A

2

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10
Q

What stage is endometrial cancer invading the serosa?

A

3A

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11
Q

What stage is endometrial cancer invading the vagina/parametrium?

A

3B

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12
Q

What stage is endometrial cancer invading the pelvic/para-aortic nodes?

A

3C

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13
Q

What stage is endometrial cancer invading the bladder/bowel/abdominal nodes?

A

4

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14
Q

What are the types of Endometrial cancer?

A

Type 1:
Endometrioid adenocarcinoma
Type 2:
Uterine serous & clear cell carcinoma (carcinosarcoma)

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15
Q

What is the most common type of endometrial cancer?

A

Type 1:

Endometrioid adenocarcinoma

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16
Q

How is type 1 endometrial cancer treated?

A

Prophylactic hysterectomy

17
Q

How is endometrial cancer treated?

A

Total abdominal hysterectomy and peritoneal washings

18
Q

What are the risk factors for endometrial cancer?

A

Post-menopause
High circulating estrogen
Atypical endometrial hyperplasia
HNPCC/Lynch type II familial cancer syndrome

19
Q

What are the typical causes of high circulating estrogen in women?

A

Obesity
Unopposed E2/Tamoxifen
PCOS
Early menarche/late menopause

20
Q

What are the symptoms of endometrial cancer?

A

Abnormal vaginal bleeding

Post-menopausal bleeding

21
Q

What is the palliative management of endometrial cancers?

A

Progesterone

Yr 3 - Reproduction (37 decks)

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