Clinical management of obesity Flashcards
Medications that cause weight gain
antidepressants - except fluoxetine
antipsychotics - especially clozapine, olanzapine
mood stabilisers - lithium
anticonvulsants - sodium valproate, carbamazepine
steroid hormones - prednisolone, dexamethasone, tamoxifene
diabetes meds - except metformin
cannabinoid derivatives
other agents - flunarizine, pizotifen, propranolol, danazol
What body system are most obesity genes related to?
the CNS
What system can be used to score obesity and what are the contributing factors?
Edmonton Obesity Staging System (EOSS)
medical, mental, functional
Describe the tier model of service delivery for obesity services
Tier 1 = population level health and obesity prevention and brief primary care interventions
Tier 2 = community-based weight management services
Tier 3 = specialist weight management services
Tier 4 = bariatric/metabolic surgery
Describe what orlistat is and what it is used for?
lipase inhibitor
used with a reduce calorie diet to aid weight loss
18-75y
one tablet with meals 3x/day
has gastro side effects
BMI>30kg/m2 or >28kg/m2 with risk factors
NHS criteria for saxenda
BMI>/=35 plus high risk diabetes (HbA1C >42) plus high risk heart disease
What is saxenda?
daily self injection
GLP-1 receptor agonist
average 7% weight loss
Underweight BMI
<18.5
Healthy weight BMI
18.5-24.9
Overweight BMI
25-29.9
Obesity class 1 BMI
30-34.9
Obesity class 2 BMI
35-39.9
Obesity class 3 BMI
> =40
What are some common health conditions that can improve after bariatric surgery?
cardiovascular disease
hypertension
idiopathic intracranial hypertension
non-alcoholic fatty liver disease with or without steatohepatitis
obstructive sleep apnoea
type 2 diabetes
