Clinical Epi. Diagnosis II Flashcards
summarize the equations for sensitivity, specificity, PPV and NPV
if the sensitivity of the test is high, most results will be ____; the number of ____ results will be low
if the sensitivity of the test is high, most results will be TP; the number of FN results will be low
if sensitivity is high then you can ____ the disease if the test comes back negative
if sensitivity is high then you can RULE OUT the disease if the test comes back negative (bc few FN; most negatives are TN)
if the specificity of the test is high, most results will be ___; the number of ___results will be low
if the specificity of the test is high, most results will be TN; the number of FP results will be low
if specificity is high, then you can ____ the disease if the test comes back positive
if specificity is high, then you can RULE IN the disease if the test comes back positive (bc few FP; most positives are TP)
summarize the rules of sensitivity and specificity
sensitivity = TP / (TP + FN)
80%
explain likelihood ratios (LR+ and LR-)
describe parallell testing vs. serial testing
- parallel testing:
- order several tests at once
- useful for rapid assessment situations
- serial testing:
- order next test on basis of prior test results
- useful in clinical situations when assessment can be done over time or tests are expensive
describe the 3 levels of prevention
- primary: reduce exposure to etiologic agent
- secondary: screen for asymptomatic disease with view of early treatment
- tertiary: prevention of recurrence or complications