Clinical Diabetes Flashcards

1
Q

What is the cause of intermittent blurry vision in DM?

A

Hyperglycemia –> lens swelling

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2
Q

The majority of people with DM have what symptoms?

A

NONE- that’s why so many are undiagnosed

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3
Q

What are the constellation of symptoms known as metabolic syndrome that serves as high predictive value for both DM and CVD?

A

High fasting glucose or pre-diabetes with hyperlipidemia and hypertension

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4
Q

What is the highest risk form of obesity?

A

Abdominal obesity

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5
Q

What is the preferred method for diagnosing diabetes?

A

HA1C

% RBCs glycosylated

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6
Q

Fast blood sugar above what level constitutes diabetes?

A

FBS >126

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7
Q

A1C above what level is diagnostic of diabetes?

A

6.5%

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8
Q

OGTT with BS above what level is diagnostic of diabetes?

A

> 200

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9
Q

Random blood sugar greater that what level is diagnostic of diabetes?

A

> 200 - with symptoms

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10
Q

What A1C constitutes pre-diabetes?

A

5.7-6.4%

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11
Q

How effective are lifestyle modifications at reducing pre-diabetes?

A

58%

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12
Q

How affected is metformin at reducing pre-diabetes?

A

31%

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13
Q

What is the target A1C level to maintain when they are diagnosed?

A

<7

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14
Q

What are the acute effects of hyperglycemia?

A

Dehydration

Immunosuppression

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15
Q

What is more dangerous, hyperglycemia or hypoglycemia?

A

Hypoglycemia can kill you

Hyperglycemia is destructive over the long run, but it’s more of a chronic problem

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16
Q

List three microvascular complications of DM

A

Retinopathy
Neuropathy
Nephropathy

17
Q

List three macrovascular complications of DM

A

MI
Stroke
PVD

18
Q

What causes retinopathy in DM?

A

Hypoxia induces expression of VEGF –> hypervascularization that destroys the retina