Clinical Conditions of the Adrenal Cortex Flashcards
Insufficient adrenal gland secretion can cause?
Primary hypoadrenalism
(Addison’s Disease)
Which hormones are insufficient in Addison’s disease?
Cortisol
Possibly Aldosterone and Androgens as well
Excess adrenal secretion can cause?
Cushing’s disease/syndrome
Conn’s Disease
Cushing’s disease/syndrome is?
Excess Cortisol
Conn’s Disease is excess ___________
Aldosterone
Primary hypoadrenalism
Addison’s disease
rare autoimmune destruction of adrenal cortex
Addison’s disease effects
Hypotension, hyperkalemia, metabolic acidosis
Hypoglycemia
Decreased sexual desire and hair in armpits/pubic area in females
Addison’s disease labs
Elevated ACTH
Elevated potassium
Decreased cortisol
Decreased sodium
Decreased glucose
Excess ACTH can indirectly cause?
Hyperpigmentation
Hyperadrenalism
Excess cortisol
Cushing’s disease/syndrome
Hyperadrenalism
Excess cortisol
Cushing’s disease/syndrome
What is the difference between Cushing’s disease and Cushing’s syndrome?
Disease is when the pituitary tumor produces too much ACTH
Syndrome is due to pharmaceutical cortisol or tumor producing cortisol
Cushing’s disease causes?
Hypertension
Hyperglycemia
Poor wound healing
Muscle wasting
Increased fat deposits
Virilization/menstrual disorders
Cushing’s disease vs Cushing’s syndrome ACTH
Disease: ACTH is increased
Syndrome: ACTH is decreased
Cushing’s disease/syndrome labs
Elevated cortisol
Increased sodium
Increased glucose
Decreased potassium
