Clinical Chemistry Flashcards
What are the components of whole blood?
whole blood, plasma, serum
What are the type of anticoagulant?
herparin, EDTA, sodium fluoride, sodium fluoride, sodium citrate
When are elevations of kidney enzymes seen?
> 75% of glomeruli of both kidneys must be nonfunctional
Azotemia
both BUN and CREA are elevated
CREA
by-product of muscle metabolism that is produced at a constant rate and filtered out almost entirely by glomeruli
UREA (urea nitrogen)
end product of protein metabolism and is excreted primarily by the kidneys
SDMA
more reliable indicator of kidney function than CREA, allowung earlier detection of acute kidney injury and chronic kidney dz
Amylase
enzyme that breaks down complex starches and glycogen
Lipase
enzyme that breaks down ling-chain fatty acids of lipids into fatty acids and glycerol
Serum pancreatic lipase immunoreactivity (PLI)
specific for the diagnosis of pancreatitis in dogs and cats
Bilirubin
insoluble molecule that comes from the breakdown of hemoglobin by the macrophages in the spleen
Total Protein (TP)
gives information about water balance in body being especially valuble for determining hydration
Albumin
one of the most important proteins in plasma/serum, major binding and transport protein in the blood, constitutes 35-50% of TP
Globulins
complex group of proteins and are usually determined by estimating the difference between TP and albumin
Alanine aminotransferase (ALT)
formerly called serum glutamic pyruvic transminase (SGPT), increases if hepatocytes are damaged or if patient is on corticosteroids or anticonvulsants
