Clinical Aspects of RA and Approach to Therapeutics Flashcards
1
Q
RA investigation
A
Immunology =>
Rheumatoid facto (IgG, IgM)
Anti cyclic citrullinated antibodies
X-ray
2
Q
Arthritis symptoms
A
Pain Stiffness Immobility Poor function Systemic Symptoms
3
Q
Clinical signs of RA
A
Swelling Tenderness Limitation of Movement (Redness) (Heat)
4
Q
Non-specific systemic features
A
Fatigue/lassitude
Weight loss
Anaemia
5
Q
Specific systemic features
A
Eyes Lungs Nerves Skin Kidneys
6
Q
Long term features of RA
A
CVS
Malignancy
7
Q
DAS
A
Disease Activity Score
8
Q
DAS clinical remission
A
<2.4
9
Q
DAS eligibility for biologic therapy
A
> 5.1
10
Q
Treatmenet of inflammatory arthritis
A
Medicines
Injections
Therapies
Surgery
11
Q
Therapeutic categories of RA
A
NSAID
DMARD
Biologics
Corticosteroids (oral, IM, IA)
12
Q
IA administration
A
Intra-articular (into a joint)
13
Q
DMARD
A
Disease Modifying Anti Rheumatic Drugs
14
Q
Commonly used DMARDs
A
Methotrexate
Sulphasalazine
Hydroxychloroquine
Leflunomide
15
Q
Biologics
A
TNFa inhibitors IL-1 inhibitors IL-6 inhibitors Anti B Cell therapies Anti T Cell therapies
