Bone and Soft Tissue Tumours Flashcards

1
Q

What is a malignant tumour arising from connective tissue?

A

Sarcoma

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2
Q

Sarcoma metastases

A

Haematogenous spread to lungs

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3
Q

Are benign or malignant tumours of the skeleton more common?

A

Benign

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4
Q

Benign bone forming tumours

A

Osteoid osteoma

Osteoblastoma

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5
Q

Malignant bone forming tumours

A

Osteosarcoma

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6
Q

Benign cartilage forming tumours

A

Enchondroma

Osteochondroma

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7
Q

Malignant cartilage forming tumours

A

Chondrosarcoma

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8
Q

Benign fibrous tissue tumours

A

Fibroma

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9
Q

Malignant fibrous tissue tumours

A

Fibrosarcoma

Malignant fibrous histiocytoma (MFH)

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10
Q

Benign vascular tissue tumours

A

Haemangioma

Aneurysmal bone cyst

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11
Q

Malignant vascular tissue tumours

A

Angiosarcoma

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12
Q

Benign adipose tissue tumours

A

Lipoma

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13
Q

Malignant adipose tissue tumours

A

Liposarcoma

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14
Q

Malignant marrow tissue tumours

A

Ewing’s sarcoma
Lymphoma
Myeloma

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15
Q

Other bone and soft tissue tumours

A

Benign, are locally destructive and can rarely metastasise - Giant Cell tumours (GCT)

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16
Q

Tumour-like lesions

A

Simple bone cyst

Fibrous cortical defect

17
Q

Investigations

A
Plain x-rays
CT
Isotope bone scan
MRI
Angiography
PET
Biopsy
18
Q

Cardinal features of malignant primary bone tumours

A
Increasing pain
Unexplained pain
Deep-seated boring nature
Night pain
Difficulty weight-bearing
Deep swelling
19
Q

Clinical features of bone tumours

A
Pain
Loss of function 
Swelling
Pathological fracture
Joint effusion
Deformity
Neurovascular effects
Systemic effects of neoplasia
20
Q

Bone tumour pain

A

Deep boring ache, worse at night

21
Q

Treatment

A

Chemotherapy
Surgery
Radiotherapy

22
Q

Common primary cancers metastasising to bone

A
Lung
Breast
Prostate
Kidney
Thyroid
GI tract
Melanoma