Cleft Lip and Cleft Palate

Question 1

cleft lip

Answer 1

• hard palate separates nasal and oral cavity (composed of the palatine and maxillary bones and skeletal muscle)
• do not have fusion of maxillary and nasal structures
• can be unilateral, bilateral, or at the mid-line

Question 2

cleft

Answer 2

• a space or opening made by cleavage or a split

- can be a slight indentation or a deep fissure

Question 3

when is the fetus most sensitive to cleft lip defect?

Answer 3

weeks 5-8 of gestation

Question 4

etiology of cleft lip and cleft palate?

Answer 4

• congenital and/or genetic
• strong link to smoking during pregnancy
• teratogens (smoking, folic acid def, viral infections)

Question 5

folic acid role and what results from a defect?

Answer 5

role: responsible for DNA replication

defect = inadeq cellular division and affects formation of various structures such as the CNS

Question 6

treatment for cleft lip

Answer 6

surgery

Question 7

relationship between cleft lip and palate?

Answer 7

they are often combined

Question 8

cleft palate

Answer 8

incomplete fusion of palatine structures

Question 9

when is the fetus most sensitive to a cleft palate defect?

Answer 9

week 9-12 in gestation

Question 10

problems with cleft palate

Answer 10

impacts nasal structures more than cleft lip does –> leads to speech, breathing and feeding issues

Question 11

statistics of babies born with cleft palate?

Answer 11

1 in 2000 live births

Question 12

treatment for cleft palate

Answer 12

surgery

Question 13

statistics of babies born with cleft lip?

Answer 13

1 in 700 live births