Classic treatments Flashcards

1
Q

ethylene glycol/methanol intoxication

A

fomepizole (aldehyde dehydrogenase inhibitor)

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2
Q

N. meningitidis

A

ceftri/penicillin, rifampin for prophylaxis

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3
Q

C. botulinum

A

anti-toxin

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4
Q

C. tetani

A

anti-toxin

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5
Q

staph aureus

A

MSSA: nafcillin
MRSA: vanco, daptomycin, linezolid, ceftaroline

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6
Q

strep pyo

A

penicillin prophylaxis

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7
Q

strep pneumo

A

penicillin/cephalosporin (systemic infection, pneumo)

vanco for meningitis

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8
Q

enterococci

A

vanco

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9
Q

H flu

A

amox clauv (mucosal), ceftri (meningitis), rifampin prophylaxis

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10
Q

legionella

A

macrolides

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11
Q

psedomonas

A

pip-tazo, AGs, carbapenems

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12
Q

syphilis

A

pen G

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13
Q

chlamydia

A

doxy (+ ceftri for gonorrhea)

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14
Q

rickettsia rickettsii

A

doxy, chloramphenicol

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15
Q

candida

A

azoles (vaginitis), nystatin, fluconazole, caspofungin (oral), add amphotericin B for systemic

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16
Q

cryptococcus

A

amphotericin B + flucytosine w/ maintenance fluconazole

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17
Q

pneumocystis jirovecii

A

TMP-SMX

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18
Q

toxo

A

sulfadiazine + pyrimethamine

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19
Q

malaria

A

primaquine (for liver hypnozoite), chloroquine, mefloquine, atovaquone/proguanil

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20
Q

trichomonas vaginalis

A

metronidazole

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21
Q

influenza

A

oseltamivir

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22
Q

CMV

A

ganciclovir, foscarnet, cidofovir

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23
Q

N. gonorrhea

A

ceftriazone

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24
Q

C diff

A

metronidazole

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25
Q

M. TB

A

RIPE

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26
Q

UTI prophylaxis

A

TMP-SMX

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27
Q

chronic HBV or HCV

A

IFN-a; ribavirin, simiprevir, sofosbuvir (HCV)

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28
Q

PDA

A

close w/ indomethacin, keep open w/ PGE analogs

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29
Q

stable angina

A

sublingual nitroglycerin

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30
Q

buerger dz

A

smoking cessation

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31
Q

GPA

A

cyclophosphamide, corticosteroids

32
Q

Kawasaki dz

A

IVIG, high dose aspirin

33
Q

temporal arteritis

A

high-dose steroids

34
Q

arrhythmia in ischemic heart tissue

A

class IB antiarrhythmic (lidocaine, mexiletine)

35
Q

pheochromocytoma

A

a-antagonists (phenoxybenzamin)

36
Q

prolactinoma

A

dopamine agonists (carbergoline/bromocriptine)

37
Q

diabetes insipidus

A

desmopressin (central) HCTZ, amiloride (nephrogenic)

38
Q

SIADH

A

fluid restriction, IV hypertonic saline

39
Q

carcinoid syndrome

A

octreotide

40
Q

DKA

A

fluids, insulin, K+

41
Q

crohn dz

A

corticosteroids, infliximab (TNF-a inhibitor), azathioprine

42
Q

UC

A

5-ASA, 6-MP, infliximab, colectomy

43
Q

hypertryglyceridemia

A

fibrate

44
Q

SS dz

A

hydroxyurea (inc HbF)

45
Q

CML

A

imatinib

46
Q

APML

A

all-trans retinoic acid

47
Q

drug of choice for anticoagulation during pregnancy

A

heparin

48
Q

heparin reversal

A

protamine sulfate

49
Q

immediate anticoagulation

A

heparin

50
Q

long-term anticoagulation

A

warfarin, dabigatran, rivaroxaban, apixaban

51
Q

warfarin reversal

A

FFP, vit K

52
Q

cyclophosphamide-induced hemorrhagic cystitis

A

mesna

53
Q

Her2/neu + breast cancer

A

trastuzumab

54
Q

osteoporosis

A

Ca/Vit D supplementation; bisphosphonates, PTH analogs, SERMs, calcitonin, denosumab

55
Q

osteomalacia/rickets

A

vit D supplementation

56
Q

chronic gout

A

xanthine oxidase inhibitors (allopurinol)

57
Q

acute gout attack

A

NSAIDS, colchicine, glucocorticoids

58
Q

migraine

A

abortive: triptans, NSAIDS
prophylaxis: propranolol, topiramate, CCBs, amitriptyline

59
Q

trigeminal neuralgia

A

carbamazepine

60
Q

tonic-clonic seizures

A

levetiracetam, phenytoin, valproate, carbamazepine

61
Q

absence seizures

A

ethosuximide

62
Q

malignant hyperthermia

A

dantrolene

63
Q

anorexia

A

nutrition, psychotherapy, mirtazapine

64
Q

alcoholism

A

naltrexone, disulfiram, acamprosate

65
Q

ADHD

A

methylphenidate, amphetamines, CBT, guanfacine, clonidine

66
Q

alcohol withdrawal

A

benzos

67
Q

bipolar disorder

A

lamotragine (atypical antipsychotics), lithium, valproic acid, carbamazepine

68
Q

hyperaldosteronism

A

spironolactone

69
Q

BPH

A

a1-antagonists (-zosins), 5a-reductase inhibitors (finasteride), PDE-5 inhibitors

70
Q

infertility

A

leuprolide, GnRH, clomiphene

71
Q

breast cancer in postmenopausal women

A

aromatase inhibitor (anastrozole)

72
Q

ER+ breast cancer

A

tamoxifen

73
Q

prostate adenocarcinoma

A

leuprolide, flutamide

74
Q

medical abortion

A

mifepristone

75
Q

erectile dysfunction

A

sildenafil, etc

76
Q

pulmonary arterial HTN

A

sildenafil, bosentan, epoprostenol