Classic labs/findings Flashcards
Anti-centromere antibodies
CREST
Anti-histone antibodies
Drug-induced SLE -> hydralazine, INH, phenytoin, procainamide
Anti-mitochondrial antibodies
Primary biliary cirrhosis -> female, cholestasis, portal HTN
Anti-platelet antibodies
ITP
Anti-topoisomerase antibodies
Diffuse scleroderma
Boot-shaped heart on X-ray
Tetrology of Fallot, RVH
Branching gram-positive rods with sulfur granules
Actinomyces israelli
Brown tumor of bone
Hyperparathyroidism -> Osteitis fibrosa cystica
Circular grouping of dark tumor surrounding pale neurofibrils
Homer-Wright rosettes -> neuroblastoma, medulloblastoma, retinoblastoma
Decreased alpha-fetoprotein
Down syndrome or other chromosomal abnormality
Desquamated epithelium casts in sputum
Curshmann’s spirals -> bronchial asthma -> whorled mucus plugs
Disarrayed granulosa cells in eosinophilic fluid
Call-Exner bodies -> granulosa-theca cells tumor of the ovary
Enlarged thyroid cells with ground-glass nuclei
Orphan Annie -> Papillary carcinoma of the thyroid
Eosinophilic cytoplasmic inclusion in the liver cells
Mallory bodies -> alcoholic liver disease
Eosinophilic cytoplasmic inclusion in the nerve cells
Lewy body
Eosinophilic globule in the liver
Councilman body -> toxic or viral hepatitis -> yellow fever
Eosinophilic inclusion bodies in cytoplasm of hippocampal nerve cells
Negri bodies of rabies
Hair on end -> crew cut on X-ray
Sickle cell, Beta-thalassemia
Granulomatous heart nodules
Aschoff bodies -> rheumatic heart disease
Hexagonal, double-jointed, needle-like crystals in bronchial secretions
Bronchial asthma -> Charcot Leyden crystals -> eosinophilic granules
Hypertension, hypokalemia, metabolic alkalosis
Conn’s syndrome
Hypochromic, microcytic anemia
1) Iron deficiency anemia
2) Lead poisoning
3) Thalassemia
Iron-containing nodules in alveolar septum
Ferruginous bodies -> asbestosis
Large lysosomal vesicles in phagocytes, immunodeficiency
Chediak-Higashi -> no phagolysosome formation
Onion skin periosteal reaction
Ewing’s sarcoma
Rhomboid crystals, positively birefringent
Pseudogout -> calcium pyrophosphate dihydrate crystals
Rib notching
Coarctation of aorta
Silver-staining spherical aggregation of tau protein in neurons
Pick bodies -> progressive dementia, changes in personality
Soap bubble in femur or tibia on x-ray
Giant cell tumor of bone -> benign
Thyroid-like appearance of kidney
Chronic bacterial pyelonephritis
Waxy casts with little urine flow
End-stage renal disease
Smudges WBCs
CLL (B-cell)
Wire loop glomerular capillary appearance on light microscopy
Lupus nephropathy
