Class 3 - Blood Flashcards
List the granular leukocytes
neutrophils, eosinophils, basophils
Red blood cells form what percentage of the formed elements of blood?
99%
RBC’s transport what percentage of CO2 in the blood?
23%
Which blood cell contains the MHC surface antigens?
WBCs
Pluripotent stem cells can develop into…
myeloid or lymphoid stem cells
60-70% of WBCs in the blood are…
neutrophils
What percentage of WBCs in the body are actually circulating in the blood?
2%
What are the agranular leukocytes?
One of these categories breaks down further into 3 different cell types, what are they?
lymphocytes and monocytes
NK cells, B cells, T cells
EPO is produced by the ____, TPO is produced by the ______
kidneys, liver
Normally, blood constitutes ___% of total body weight
8%
All offspring of lymphoid stem cells are ____, but not all (same thing) come from lymphoid stem cells. Which (same thing) is of myeloid stem cell origins?
agranular leukocytes
monocytes
What is the function of albumins, globulins, and fibrinogen (each)?
albumins - regulating osmotic pressure
globulins –> immunoglobulins
fibrinogen - blood clotting (fibrin)
Hemopoiesis occurs in the…
red bone marrow
What function do cytokines have in hemopoiesis?
they promote the proliferation of progenitor cells in the red bone marrow
What is a reticulocyte?
an immature RBC with the nucleus already discarded
The lifespan of a RBC is roughly…
120 days
What is the main stimulus of erythropoiesis? Why?
hypoxia –> kidneys release EPO
What is the precursor cell to RBCs?
pro-erythroblasts
Which WBC makes up the least percentage of leukocytes in the blood?
basophils
Which WBCs are associated with allergic reactions?
eosinophils + basophils
Which WBCs are associated with bacterial infections?
neutrophils
Which WBCs are associated with viral infections?
monocytes
Which WBCs are associated with parasitic infections?
eosinophils
What are the three mechanisms of hemostasis?
vascular spasm
platelet plug formation
coagulation
How is hemolytic disease of the newborn, caused by Rh incompatibility, treated?
blood transfusion via umbilical vein (intrauterine)
blood exchange transfusion after birth
intravenous immunoglobin to help the baby’s immune system
Which type of hormone promotes proliferation of progenitor cells in RBM?
cytokines
What percentage of WBCs are actually circulating in the blood?
2%