Class 3 - Blood Flashcards

1
Q

List the granular leukocytes

A

neutrophils, eosinophils, basophils

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2
Q

Red blood cells form what percentage of the formed elements of blood?

A

99%

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3
Q

RBC’s transport what percentage of CO2 in the blood?

A

23%

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4
Q

Which blood cell contains the MHC surface antigens?

A

WBCs

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5
Q

Pluripotent stem cells can develop into…

A

myeloid or lymphoid stem cells

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6
Q

60-70% of WBCs in the blood are…

A

neutrophils

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7
Q

What percentage of WBCs in the body are actually circulating in the blood?

A

2%

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8
Q

What are the agranular leukocytes?

One of these categories breaks down further into 3 different cell types, what are they?

A

lymphocytes and monocytes

NK cells, B cells, T cells

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9
Q

EPO is produced by the ____, TPO is produced by the ______

A

kidneys, liver

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10
Q

Normally, blood constitutes ___% of total body weight

A

8%

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11
Q

All offspring of lymphoid stem cells are ____, but not all (same thing) come from lymphoid stem cells. Which (same thing) is of myeloid stem cell origins?

A

agranular leukocytes

monocytes

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12
Q

What is the function of albumins, globulins, and fibrinogen (each)?

A

albumins - regulating osmotic pressure
globulins –> immunoglobulins
fibrinogen - blood clotting (fibrin)

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13
Q

Hemopoiesis occurs in the…

A

red bone marrow

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14
Q

What function do cytokines have in hemopoiesis?

A

they promote the proliferation of progenitor cells in the red bone marrow

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15
Q

What is a reticulocyte?

A

an immature RBC with the nucleus already discarded

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16
Q

The lifespan of a RBC is roughly…

A

120 days

17
Q

What is the main stimulus of erythropoiesis? Why?

A

hypoxia –> kidneys release EPO

18
Q

What is the precursor cell to RBCs?

A

pro-erythroblasts

19
Q

Which WBC makes up the least percentage of leukocytes in the blood?

A

basophils

20
Q

Which WBCs are associated with allergic reactions?

A

eosinophils + basophils

21
Q

Which WBCs are associated with bacterial infections?

A

neutrophils

22
Q

Which WBCs are associated with viral infections?

A

monocytes

23
Q

Which WBCs are associated with parasitic infections?

A

eosinophils

24
Q

What are the three mechanisms of hemostasis?

A

vascular spasm
platelet plug formation
coagulation

25
Q

How is hemolytic disease of the newborn, caused by Rh incompatibility, treated?

A

blood transfusion via umbilical vein (intrauterine)
blood exchange transfusion after birth
intravenous immunoglobin to help the baby’s immune system

26
Q

Which type of hormone promotes proliferation of progenitor cells in RBM?

A

cytokines

27
Q

What percentage of WBCs are actually circulating in the blood?

A

2%