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2500 > Class 3 & 4 - Pharmacology > Flashcards

Class 3 & 4 - Pharmacology Flashcards

1
Q

Bioavailability

A

how much drug is available to enter the cell

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2
Q

Chemical Name

A

description of the drug using the nomenclature of chemistry

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3
Q

Side Effect

A

a reaction to a drug that is known

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4
Q

Toxicity

A

degree of detrimental physiologic effects caused by excessive drug dosing

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5
Q

Indication

A

medical conditions for which the drug is given

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6
Q

Pharmacodynamics

A

what the drug does to the body

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7
Q

First Pass Effect

A

rapid hepatic inactivation of certain oral drugs; drug is completely inactivated

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8
Q

Absorption

A

movement of drug from its site of administration into the blood

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9
Q

Toxic Concentration

A

detrimental physiologic effects from excessive drug dose

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10
Q

Partial Agonist

A

mimic the action of endogenous regulatory molecules but at a lower level than agonists

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11
Q

Average Lethal Dose

A

dose that is lethal to 50% of the population

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12
Q

Drug Schedule

A

schedule 1, 2, 3, unscheduled

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13
Q

Generic Name

A

less complex than chemical names and is the name of the drug we most commonly use

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14
Q

Adverse Effect

A

undesired effect that occurs at normal drug doses

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15
Q

Hepatotoxicity

A

drugs that undergo metabolism and are converted to toxic products that can injure liver cells

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16
Q

Contraindication

A

conditions not to give the drug

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17
Q

Ions

A

molecules that have a net electrical charge that is either positive or negative

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18
Q

Polar Molecules

A

have an uneven distribution of charge but is overall neutral

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19
Q

Distribution

A

drug movement from the blood to the interstitial space and then to cells

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20
Q

Therapeutic Range

A

the range where the drug will have it effect

21
Q

Average Effective Dose

A

ED50

22
Q

Therapeutic Index

A

measure of a drugs safety; the higher the safer

23
Q

OTC

A

over-the-counter

24
Q

Trade Name

A

names under which the drug is marketed, e.g. Tylenol

25
Q

Paradoxical Effect

A

opposite effect of what is expected

26
Q

Nephrotoxicity

A

detrimental physiologic effects from excessive drug dose in the kidneys

27
Q

Relative Contraindication

A

weigh the risks and the benefits

28
Q

Ionization

A

attraction to the opposite charge

29
Q

Metabolism

A

chemical alteration of the drug structure; occurs mainly in the liver

30
Q

Minimum Effective Concentration

A

the minimum concentration required for the drug to have therapeutic effects

31
Q

Teratogenic

A

drug-induced birth defect

32
Q

Selectivity

A

a drug that only does what we want it to with no side effects

33
Q

PRN

A

“as needed”

34
Q

Idiosyncratic Effect

A

uncommon drug response due to genetic predisposition

35
Q

Ototoxicity

A

detrimental physiologic effects from excessive drug dose that affects hearing

36
Q

Pharmacokinetics

A

how drugs move throughout the body

37
Q

pH Partitioning/Ion Trapping

A

molecules will accumulate on the side where the pH most favours their ionization

38
Q

Antagonist

A

inhibit the action of endogenous regulatory molecules

39
Q

Excretion

A

removal of drugs from the body; done primarily by the kidneys

40
Q

Agonist

A

mimic the action of endogenous regulatory molecules

41
Q

Rate of Absorption

A

how soon effects will occur

42
Q

Amount of Absorption

A

how intense effects will be

43
Q

Schedule 1

A

all prescription medications

44
Q

Schedule 1; Schedule F

A

meds with no potential for abuse

45
Q

Schedule 1; Schedule G

A

meds that have the potential for abuse; are controlled

46
Q

Schedule 1; Schedule G; Narcotics

A

morphine, codeine

47
Q

Schedule 2

A

all non-prescription medications that are monitored by a pharmacist

48
Q

Schedule 3

A

all other non-prescription medications sold in pharmacies; OTC

49
Q

Unschedules

A

non-prescription meds sold in ANY store

2500 (12 decks)

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