Chronobiology Flashcards
What brain damage would destroy your endogenous clock?
Hypothalamus
Where is our endogenous clock?
In the suprachiasmatic nucleus
How is the SCN externally regulated?
By light in the melanopsion ganglional cells in the retina
What is PRC and by what is it affected?
Phase response curve, light, especially blue light
How is the misalignment with the social time and biological time called?
Social jetlag
How do you record brain activity during sleep?
Polysomnography
What does a polysomnography record?
brain activity, muscle activity, eye movements
How are the following characteristics in order for NREM?
1) cortical EEG
2) muscle tone
3) eye movements
4) breathing
5) heart rate
6) thermoregulation
7) dreaming
1) high amplitude
2) low, ‘constant’
3) none
4) deep, regular
5) low, regular
6) good
7) +
How are the following characteristics in order for REM?
1) cortical EEG
2) muscle tone
3) eye movements
4) breathing
5) heart rate
6) thermoregulation
7) dreaming
1) as waking
2) none, ‘twitches’
3) frequent
4) fast, irregular
5) fast, irregular
6) poor
7) +
how much does a NREM-REM cycle last?
90-100 minutes
When do you get more REM sleep?
At the end of the night
What does the two-process model of sleep regulation contain?
a homeostatic process S (the need for sleep)
a circadian process C (the endogenous clock)
What do S and C determine?
The timing of sleep
How does age impact sleep?
Shorter, fragmented sleep, sleeping and waking up earlier, more often sleep disorders
What is the rate for resencronizing to anew time zone?
1h/ day
