chronic kidney disease Flashcards

0
Q

CKD is defined as

A

GFR less than 60 for > 3 months

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1
Q

as the number of functioning neprhons decreases

A

more demand per nephron

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2
Q

CGA staging

A

cause
gfr
albuminuria

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3
Q

to figure out eGFR you must

A

use the serum certaine and GFR, NOT creatinine alone

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4
Q

preferred scale for adults

A

albumn/creatinne

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5
Q

preferred scale for kids

A

protein/creatinine

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6
Q

low GFR

A

is more than high albumin

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7
Q

pathological progression CKD

A

tubular atrophy
interstitial fibrosis
glomerular sclerosis
periglomerual fibroiss

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8
Q

assessing proteinuria

A

do a spot urine same (in AM for kids) if increased risk for CKD do alumin specific dipstick for ACR for adults or a PCR for kids

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9
Q

interventions for CKD

A
low protein diet
oral alkali
hyperuricemia-->allopurinol
lipids and treatment
vit d analogs
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10
Q

comorbidities of CKD

A
HTN
anemia
vit d def
po4 retnetion
metabolic acidosis
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11
Q

preferred agents for HTN CKD

A

acei or arb

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12
Q

cautions of HTN in CKD

A

10-20% CREATININEb increase may happen in first 2 weeks, but than stabilizes unless some other issue

NO K supplements and k sparing diuretics

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13
Q

why do patients get anemia

A

ckd–>decrease epo production by peritubular cells

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14
Q

vit d def and PO4 retnetion lead to

A

hypo ca–>hyperpth–>osteodystrophy

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15
Q

even pth may not be enough to

A

correct PO4

16
Q

treatment of vitd def and po4 retention

A

decrease dietary po3 or use po4 chelators

vit d supplements to tx bone pain

17
Q

chronic metabolic acidosis

A

treat with Na-citrate or NaHCo3

milk seems to help

18
Q

start dialysis at stage

A

4