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Physio Midterm > Chp 5 Physio > Flashcards

Chp 5 Physio Flashcards

1
Q

What are the 2 Body fluid compartments

A

1.ICF = 2/3 of total body water
2. Ecf = 1/3 total body of water

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2
Q

ECF Consists of

A
  1. Interstitial fluid (IF) 75%
  2. Blood plasma 25%
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3
Q

Homeostasis ____________ Mean Equilibrium

A

DOES NOT

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4
Q

What is Osmotic Equilibrium

A

Concentration of H20
ICF & ECF is EQUAL

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5
Q

What is Chemical Disequilibrium

A

Components ( molecular components)

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6
Q

What is Electrical Disequilibrium

A

Charge
ICF IS MORE ( - )
ECF is more ( + )

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7
Q

What is the Concentration of Blood

A

300 mosm

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8
Q

K+

A

Potasssium

  • abundant in ICF (IONS)
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9
Q

Na+

A

Sodium
Abundant in ECF (IONS)

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10
Q

2 kinds of Transport Membranes

A

Active & Passive

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11
Q

Active Transport needs

A

ATP

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12
Q

3 TYPES OF ACTIVE TRANSPORT

A
  1. DIRECT/PRIMARY
  2. INDIRECT/SECONDARY
  3. VESICULAR Transport
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13
Q

Vesicular Transport consists of

A

1.) Exocytosis (ECF)

  1. ) Endocytosis ( ICF)

3.) Phagocytosis

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14
Q

Goal of passive transport is _________________

A

To reach equilibrium

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15
Q

Passive transport DOES or DOES NOT require ATP

A

Does not require ATP

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16
Q

Passive transport is driven by

A

Concentration Gradient

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17
Q

3 types of passive transport

A
  1. Facilitated diffusion
  2. Osmosis
  3. Simple diffusion
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18
Q

Osmosis is

A

Movement of H2O across a membrane

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19
Q

Do males or females have more percentage of h20

A

Males

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20
Q

Osmotic Pressure is

A

Force generated by movement of h20

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21
Q

In Osmosis what direction does the concentration gradient move with solutes?

A

Low concentration solutes to high concentration solutes

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22
Q

Osmosis for h20

A

High concentration of h20 to low concentration of h20

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23
Q

Tonicity is

A

Describes the volume change of a cell depending on concentration

  • non penetrating solutes
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24
Q

Tonicity

3 kinds of solutions

A
  1. ISOTONIC
  2. HYPERTONIC
  3. HYPOTONIC
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25
Q

Isotonic means

A

NO CHANGE

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26
Q

HYPERTONIC CAUSES CELLS T0 ____________

A

SHRINK

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27
Q

HYPOTONIC CAUSES CELLS TO ___________

A

SWELL

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28
Q

TONICITY only depends on the concentration of

A

Non-penetrating solutes

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29
Q

7 points to describe Simple Diffusion

A
  1. Movement of solutes is from High concentration to low concentration of solutes
  2. Movement continues until concentration is EQUAL
  3. Rapid over short distances
  4. Directly related to temperature
  5. Inversely related to molecular size and weight (Smaller = faster diffusion)
  6. Can happen in an open system or across a partition
  7. LIPID SOLUABLE, GASES
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30
Q

What is Fick’s Law ?

3 points

A

Rate of Diffusion directly proportional

  • Surface area
    -membrane permeability
    -concentration gradient is larger
31
Q

7 General properties of diffusion

A
  1. Diffusion of kinetic energy
  2. Molecules diffuse from one area of high concentration of solutes to low concentration of solutes
  3. Continues until concentrations come to equilibrium
  4. Shorter distances
  5. Higher temps
  6. Smaller molecules
  7. Open system
32
Q

What is Facilitated diffusion “Protein mediated transport”
Require atp?

What direction of solutes ?

And …..

A

No atp
High concentration of solutes to low concentration of solutes

Specifity
Competition
Saturation

33
Q

The main membrane protein we need to know

A

Transport protein

34
Q

Transport Proteins have two proteins, they are called?

A

Channel Proteins
Carrier Proteins

35
Q

Channel Proteins

A

Open water filled passageways

A. Open channels ( leak )
B. Gated Channels - can be open or closed

36
Q

Open channels are (leak)

A

Always open

37
Q

Carrier Proteins

A

Changes confirmation ( shape )
A. Uniport
B. Symport
C. Antiport

38
Q

What is Antiport?

A

Moves substrate in opposite direction

39
Q

What is Symport ?

A

2 or more substrate moves same direction

40
Q

What is Uniport ?

A

1 kind of substrate, same direction

41
Q

What does Active Transport do ?

A

Moves substances AGAINST their concentration gradients

42
Q

2/3 total body of water

A

ICF

43
Q

Primary ( DIRECT) active transport uses what ?

Does it require atp?

A

Uses sodium potassium pump
Uses ATP directly

44
Q

Na+- K+-Atpase

A

Sodium potassium pump

45
Q

Abundant in your ICF

A

K+

46
Q

Active transport you need

A

ATP

47
Q

What does your Secondary ( indirect ) transport do?

A

Uses potential energy to move against gradient

does not use atp directly

48
Q

Potential energy is

A

Stored energy

49
Q

Movement of water across a membrane

A

Osmosis

50
Q

Vesicular Transport

A

Endocytosis
Exocytosis
Phagocytosis

51
Q

Phagocytosis

A

Combine with lysosomes “cell eating” “cell death”

52
Q

Describe volume change of a cell

A

Tonicity

53
Q

Concentration of solutes in osmosis move in what direction

A

Is low to high

54
Q

Phagocytosis functions

A

Immunity
Recycling

Found in white blood cells

55
Q

Exocytosis requires ?

And where does it move molecules?

A

Requires ATP & Calcium
Moves molecules outside the cell
Mostly used for protein release

56
Q

Exocytosis is where?

A

Outside of the cell

57
Q

Where is Endocytosis

A

In cell

58
Q

Endocytosis moves molecules where?

What does it require?

Is it selective?

A

Moves molecules into the cell
Requires energy from atp
Non selective, allowing ecf to enter cell

59
Q

Which transport moves substances against their concentration gradients

A

Active transport

60
Q

Concentration gradient moves your solutes in what direction

A

Movement from high concentration of solutes to low concentration of solutes

61
Q

Membrane permeability is directly related

A

To lipid solubility

62
Q

Membrane permeability is inversely related to

A

Molecular size

63
Q

The Goal to reach equilibrium is

A

Passive transport

64
Q

Abundant in ECF

A

NA+ (sodium)

65
Q

Cause cell too swell

A

Hypotonic

66
Q

What is it called?

Depending on the concentration of non penetrating solutes describes the volume change

A

Tonicity

67
Q

2 or more substrates moves in same direction

A

Symport

68
Q

1 kind of substrate, same direction

A

Uniport

69
Q

Name the Gated channels

A

Voltage
Chemical
Mechanical

70
Q

Moves substrate in opposite direction

A

Antiport

71
Q

Always open ( leak ) is also called

A

Open channels

72
Q

Voltage, chemical & mechanical are what channels

A

Gated channels

73
Q

Specificity , competition and saturation are included in what diffusion

A

Facilitated diffusion

74
Q

Components, molecular components

A

Chemical disequilibrium

Physio Midterm (6 decks)

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