Chp 40 Endocrine Disorder

Question 1

Name 3 thyroid hormone (4)

Answer 1

1. Levothyroxine
2. Thyroid
3. Liothyronine
4. Liotrix

Question 2

What’s the pharmacological action of thyroid hormones?

Answer 2

They’re synthetic forms of the thyroid hormone. They increase the metabolic rate, protein synthesis, CO, renal perfusion, O2 use, body temp ,blood volume

Question 3

What are two antithyroid medications?

Answer 3

1. Proplthiouracil

2. Methimazole

Question 4

What are two therapeutic uses of radioactive iodine?

Answer 4

It’s used to treat hyperthyroidism and thyroid cancer.

Question 5

What is the pharmacological action of radioactive iodine?

Answer 5

It’s absorbed by the thyroid and destroys some of the thyroid producing cells.

Question 6

What is the pharmacological action of strong iodine solution?

Answer 6

It creates high levels of iodine, and reduces iodine uptake by the thyroid gland, and inhibits thyroid hormone production.

Question 7

Name a growth hormone

Answer 7

Somatropin

Question 8

Expected pharmacological action of somatropin?

Answer 8

It stim overall growth and protein production, and decrease the use of glucose.

Question 9

Name two antidiuretic hormones

Answer 9

-pressin

vasopressin, desmopressin

Question 10

What’s the action of antidiuretic hormone?

Answer 10

• promotes re-absorption of water within the kidney

- vasoconstriction because of vascular smooth muscle contraction.

Question 11

What are two adverse effects of ADH?

Answer 11

• Re absorption of too much water

- MI from excessive vasoconstriction

Question 12

Name 2 adrenal hormone replacements

Answer 12

1. hydrocortisone
2. prednisone, dexamethasone
3. Mineral corticoids: fludrocortisone

Question 13

What are 2 therapeutic uses of adrenal hormone replacement?

Answer 13

1. Replacement therapy for adrenocortical insufficiency (Addison’s disease)
2. Nonendocrine disorders