Chp 11 Flashcards
The principles underlying complications of drug therapy in older adults include?
polypharmacy, altered pharmokinetics, poor adherence, and multiple illnesses (select all that apply)
Altered absorption of drugs in older adults may result in what kind of drug response?
adverse
The four major factors that can alter drug distribution in older adults?
increased body fat, decreased lean muscle mass, decreased body water, and reduced concentration serum albumin ( select all that apply)
Because of reduced albumin levels protein binding of drug decreases causing?
the level of free drug to rise
The most important cause of adverse drug reactions in the older adult is?
drug accumulation which causes decreased renal and kidney function
In the older adult, the proper index of renal function is the ?
Creatinine Clearance, BUN
Factors underlying the increase in adverse reactions in the geriatric population include?
Illness, polypharmacy, poor adherence, multiple pathologies, inadequate supervision, dangerous drugs