Chap 4

Question 0

Factors that affect drug absorption include

Answer 0

Rate of dissolution, surface area(diabetes), blood flow, lipid solubility and Ph partitioning

Question 1

For a drug to penetrate membranes directly it must be?

Answer 1

Lipid soluble

Question 2

What drugs dissolve in the intestine rather then the stomach?

Answer 2

Enteric coated

Question 3

Most drug metabolism takes place?

Answer 3

Liver

Question 4

How do we reduce fluctuations in drug levels?

Answer 4

Administering drugs by continuous infusion

Question 5

The therapeutic range of a drug lies between?

Answer 5

Minimum effective dose and toxic concentration

Question 6

What accounts for most drug excretion?

Answer 6

Kidneys

Question 7

What is sentenal vent ?

Answer 7

Extreme error that results in a death

Question 8

Hematocrit is always how many times as large as hemoglobin?

Answer 8

3x

Question 9

HGB level

Answer 9

Female 12-16

Male 14-17

Question 10

Hematocrit?

Answer 10

Male 41-51 percent

Question 11

Bicarbonate?

Answer 11

22-28 meq/L

Question 12

PH?

Answer 12

7.35-7.45

Question 13

Pco2?

Answer 13

35-45 mm Hg

Question 14

PO2

Answer 14

80-100 mm Hg

Question 15

BUN?

Answer 15

8-20 mg\dl

Question 16

Creatinine?

Answer 16

0.7-1.3 mg/dl

Question 17

Sodium?

Answer 17

136-145 meq/L

Question 18

Potassium?

Answer 18

3.5-5.0 meq/L

Question 19

Chloride?

Answer 19

98-106 meq\L

Question 20

Pharmacokinetics is?

Answer 20

Drug interaction across the membrane
Polar
Cross blood brain barrier
Lipid soluble (Dilantin, seizure meds)

Question 21

Polar molecules are

Answer 21

Uneven distribution of a charge

No net charge

Question 22

Ions are?

Answer 22

Molecules that have a net charge