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Pharmacology > Cholinergic Pharm > Flashcards

Cholinergic Pharm Flashcards

1
Q

What does M3 do to the glands

A

increase all secretions

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2
Q

What does M3 do to the eye

A

contraction :miosis of sphincter papillae

contraction : accommodation for near vision- ciliary muscle

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3
Q

What does M2 do to the heart

A

affects the SA & AV node

decreased rate of firing

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4
Q

What does M3 do to the lungs

A

Bronchospasm

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5
Q

What does M3 do to the GI/ GU systems

A

increase gut motility
increased voiding
detrusor contraction
trigone relaxation

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6
Q

What does M3 do to blood vessels

A

dilation via NO

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7
Q

Methacholine

A

Dx: brachial hyperactivity

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8
Q

Bethanechol

A

Tx: paralytic ileum & urinary retention

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9
Q

Carbachol

A

used as a miotic agent

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10
Q

Pilocarpine

A

Used for glaucoma

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11
Q

Rivastigmine

A

Alzheimer

Parkison

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12
Q

Donezepil

A

Alzheimer

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13
Q

Endrophonium

A

Ddx of myasthenia graves

Ddx cholinergic crisis

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14
Q

Neostigmine

Pyridostigmine

A

Tx: myasthenia gratis
reversal of competitive
postoperative GI/GU retention

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15
Q

Physostigmine

A

tx :atropine overdose

crosses BBB

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16
Q

Atropine

A 
anticholinergic 
Tx: antispasmodic 
anti secretory 
management of Achase inhibitor overdose 
antidiarrheal 
Opthalmology 
reverse Av block
17
Q

Troppicamide, Homatropin, cyclopentolate

A

Ophthalmology

18
Q

Iprtropium , Tiotropium

A

Asthma, COPD

19
Q

Scopolamine

A

motion sickness

20
Q

Benztropine, trihexyphenidyl

A

Parkinsonism

has extrapyramidal side effects with antipsychotics

21
Q

Oxybutynin, tolterodine

A

bladder spasm

urinary incotinience

22
Q

Dicyclomine

A

irritable bowel syndrome

23
Q

Varenicline

A

smoking cessation

24
Q

Succinylcholine

A

neuromuscular blocker

25
Q

What are the two ganglion blockers

A

hexamethonium & mecamylamine

26
Q

What are the tissues affected & the effects by Alpha 1

A

arterioles : increase TPR
veins: increase preload

radial muscle: constriction and mydriasis

Kidney: decrease renin

Liver: increase glycgenolysis

Genitourinary:
-bladder : increase sphincter tone , urinary retention

Vas deferens: increase emission

27
Q

What are the tissues effects of alpha 2

A

decrease release of Ne at the synapse

decrease insulin

aggregation of platelets

28
Q

What is the effects of Beta 1

A

SA,AV: increase HR
muscle: increase contractility , increase SV

Kidney: increase renin

ciliary body : increase aqueous humour

29
Q

What are the effects of Beta 2

A

vessels: vasodilation , decreased TPR
bronchioles: bronchodilation
uterus: relaxation

Liver & adipose:lipolysis, glycogenolysis, gluconeogenesis

Pharmacology (15 decks)

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