Adrenergic Pharm Flashcards
Phenylephrine
nasal contestant
mydriatic - dilation of the eyes
pure alpha 1
Mephentermine, Metaraminol, midodrine
Hypotension (in spinal anesthesia)
Isooroterenol
B1=B2
TX: bradychardia, Asthma
Dobutamine
B1
Acute CHF management
can determine areas of ischemia in stress testing
Terbutaline
B2
Asthma
premature labor
Epinephrine
alpha 1< B1
at high doses it has a alpha effect
at low doses it has a beta effect
What are the effects of alpha 1
vasoconstriction ( veins & arteries
mydriasis- pupil dilation
smooth muscle constriction
What are the effect of alpha 2
decrease lipolysis
decrease insulin
decrease synaptic release
decrease aqueous humour
What are the effects of beta 1 & 2
increase HR & contractility increase renin increase insulin increase gluconeogenesis increase lipolysis decrease potassium increase aqueous humour
Clonidine, Methylfopa
Hypertension
Apraclonidine, Brimonidine
Glaucoma
Tizanidine
Muscle relaxant
Phenoxybenzamine
Pheochromocytoma
Phentolamine
Hypertension
blocks alpha 1 & 2 –> vasodilation
tx: cocaine overdose
Zosins
Hypertension
BPH